Search for dissertations about: "SMD"

Showing result 1 - 5 of 14 swedish dissertations containing the word SMD.

  1. 1. Chemical attenuation of bacterial virulence : small molecule inhibitors of type III secretion

    Author : Anna Kauppi; Mikael Elofsson; Anders Karlén; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistance; virulence; type III secretion; T3SS inhibitors; Yop; SMD; QSAR; screening; Yersinia pseudotuberculosis; Organic chemistry; Organisk kemi;

    Abstract : Despite the large arsenal of antibiotics available on the market, treatment of bacterial infections becomes more challenging in view of the fact that microbes develop resistance against existing drugs. There is an obvious need for novel drugs acting on both old and new targets in bacteria. READ MORE

  2. 2. Simulation of Combustion and Mixture Formation for Gasoline Direct Injection Engine Application

    Author : Chen Huang; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; VSB2; Reitz-KHRT; gasoline surrogate; LISA; sensitivity study.; Reitz-Diwakar; Trajectory collision; laminar flame speed; chemical kinetics; TAB; Rosin-Rammler; ignition delay; OpenFOAM; ethanol; O Rourke collision; SMD; hollow cone spray; liquid penetration;

    Abstract : The development and introduction of new engine technologies are primarily motivated by the need to comply with increasingly stringent emissions legislation and to reduce fuel consumption. One of the most important of these new engine technologies is direct gasoline injection, which is considered to be an important and cost-effective measure to meet both targets. READ MORE

  3. 3. Numerical Modelling of Fuel Injection and Stratified Turbulent Combustion in a Direct-Injection Spark-Ignition Engine Using an Open Source Code

    Author : Chen Huang; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; hollow-cone spray; KHRT; liquid penetration; CFD; OpenFOAM; Flame Speed Closure FSC ; ignition delay; SMD; gasoline surrogate; laminar flame speed; presumed PDF; Spray-Guided Gasoline Direct Injection engine; chemical mechanism; modelling; premixed stratified turbulent combustion;

    Abstract : Stringent regulations on the emission of pollutants, especially carbon dioxide (CO2), necessitate the development of advanced combustion technologies. Gasoline direct injection (GDI) into the combustion chamber of a Spark Ignition (SI) engine is a combustion strategy that is widely recognized as having the potential to improve fuel efficiency of internal combustion engines for passenger cars. READ MORE

  4. 4. Neuroimaging biomarkers in Alzheimer’s disease

    Author : Farshad Falahati Asrami; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Alzheimer’s disease (AD) is characterized by an accumulation of abnormal plaques and tangles in the brain, a process that is estimated to begin years before the appearance of clinical symptoms. Individuals with subjective memory decline (SMD) or mild cognitive impairment (MCI) run a higher risk of developing AD than cognitively normal (CN) people. READ MORE

  5. 5. Determinants of peptidyl-tRNA drop-off from E. coli Ribosomes : Effects of antibiotics, mutations and translation factors

    Author : Reza Karimi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : During protein synthesis, some peptidyl-tRNA molecules dissociate from the ribosomes and become hydrolysed by peptidyl-tRNA hydrolase (Pth). Two different in vitro systems, poly(U) and natural mRNA programmed ribosomes, have been used in order to determine dissociation (drop-off) rates of deacylated- and peptidyl-tRNAs from different sites on ribosomes. READ MORE