Search for dissertations about: "SREBP-1"

Found 3 swedish dissertations containing the word SREBP-1.

  2. 1. Growth hormone and PPARalpha in the regulation of genes involved in hepatic lipid metabolism

    Author : Caroline Améen; Göteborgs universitet; []
    Keywords : Growth hormone; insulin; SREBP-1; lipogenic enzymes; microsomal triglyceride transfer protein; PPARalpha; LXRalpha; triglycerides; liver;

    Abstract : Growth hormone (GH) plays a key role in the regulation of lipid and lipoprotein metabolism. Its sexually dimorphic secretory pattern regulates many sex-differentiated functions in the liver, such as triglyceride synthesis and VLDL secretion. READ MORE

  4. 2. The role of GH in the regulation of energy homeostasis, lipid metabolism and cardiovascular function in transgenic mice

    Author : Bob Olsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth hormone; cardiovascular disease; energy homeostasis; lipid metabolism; transgenic mice;

    Abstract : The aim of this thesis was, using two transgenic models, to investigate some metabolic diseases associated with acromegaly e.g. hypertension and alterations in lipid and lipoprotein metabolism. READ MORE

  5. 3. Molecular regulation of microsomal triglyceride transfer protein gene, MTP : functional genetic studies in relation to cardiovascular disease

    Author : Helena Ledmyr; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Microsomal triglyceride transfer protein; polymorphism coronary heart disease; CHD; cardiac lipid metabolism; protein function; functional promoter studies;

    Abstract : The microsomal triglyceride transfer protein, MTP, is expressed mainly in the liver, intestine and in the heart. It is crucial for the assembly and secretion of apob-containing lipoproteins, chylomicrons in the intestine and very-low density lipoproteins (VLDL) in the liver. READ MORE