Search for dissertations about: "STABILITY STUDIES OF DRUGS"
Showing result 16 - 20 of 68 swedish dissertations containing the words STABILITY STUDIES OF DRUGS.
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16. Molecular pharmacology of amiodarone
Abstract : Amiodarone (Am) is a potent class III antiarrhythmic drug. Its use is limited due to serious side effects and it was therefore used only when other therapeutic interventions proved to be ineffective. READ MORE
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17. Structural and functional studies of C4b-binding protein (C4BP)
Abstract : The subject of this thesis is complement inhibitor C4b-binding protein (C4BP), on which we have performed both structural and functional studies. Complement is part of the innate immune defence and eliminates microbes, solubilises immune complexes and is involved in the clearance of apoptotic cells. READ MORE
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18. Methods for structural studies of an antibody, screening metabolites in rat urine and analysis of spent cell cultivation media using LC/ESI-MS and chemometrics
Abstract : This thesis describes bioanalytical methods for generating fingerprints of biological systems for extracting relevant information with (protein) drugs in focus. Similarities and differences between samples can reveal the hidden relevant information, which can be used to optimize the production and facilitate the quality control of such protein drugs during their development and manufacture. READ MORE
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19. Advanced Methods for Evaluation of the Performance of Complex Drug Delivery System
Abstract : Low oral bioavailability of drugs originating from poor aqueous solubility is a common issue in drug development. Various enabling formulations have been presented to circumvent this limitation, many making use of supersaturation. In these, the drug is delivered to the gastro-intestinal lumen in a high energy state e.g. READ MORE
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20. Identification and Forensic Classification of Amphetamine
Abstract : Amphetamine is one of the most abused drugs worldwide. In the fight against the manufacture and illegal distribution of amphetamine, the contribution from forensic laboratories is the identification of the drug and the establishment of links between seizures. These links contribute to the disclosure of distribution chains and illicit laboratories. READ MORE