Search for dissertations about: "STEM"
Showing result 1 - 5 of 1497 swedish dissertations containing the word STEM.
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1. Stem cell function and organ development : analysis of Lhx2 function in hematopoietic stem cells and eye development
Abstract : When a multicellular organism suffers damages to tissues/organs it heals itself by either substituting the lost cellular matrix by scar formation or by regenerating the lost tissue. Regeneration likely occurs by a recapitulation of the developmental process that formed the organ. READ MORE
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2. Allogeneic stem cell transplantation : patients’ and sibling donors’ perspectives
Abstract : Allogeneic haematopoietic stem cell transplantation (hereafter HSCT) is an established treatment which offers a potential cure for a variety of diseases, mainly haematological malignancies. However, the treatment is also associated with significant risks of acute complications and late side effects, including mortality. READ MORE
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3. Human embryonic stem cells for bone engineering applications
Abstract : The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and repair therapies are needed in a large number of clinical cases. READ MORE
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4. Stem cell based therapy of malignant brain tumors
Abstract : Malignant brain tumor is a highly invasive and vascularized cancer. Current forms of therapy are not curative and can, at best, prolong survival for patients with this disease. The mean survival is only around 15 months. READ MORE
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5. Regulation of Hematopoietic Stem Cells
Abstract : This thesis is about the regulation of hematopoietic stem cells (HSCs) that represent rare cells residing in the bone marrow (BM) of adults. They are multipotent cells that have the capacity to differentiate to all mature cells of the blood system and have the capacity to self-renew, i.e. generate new HSCs. READ MORE