Search for dissertations about: "SYCP3"

Found 2 swedish dissertations containing the word SYCP3.

2. 1. The fate of primary aneuploid cells in early embryonic development and stem cells

   Author : Daniel Aaron Lightfoot; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Mosaic; aneuploid; embryo; gastrulation; ES cell; SYCP3;

   Abstract : Chromosomal aberrations occurring during gametogenesis and early embryonic development play a significant role in infertility and fetal loss in humans. Germ cells that have an abnormal number of chromosomes (aneuploidy) are generated mainly due to errors during female gamete formation, a phenomenon increasing in occurrence with age. READ MORE

4. 2. Molecular architecture of meiotic chromosomes

   Author : Ivana Novak; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Meiosis; Chromosome architecture; Synaptonemal complex; Cohesin complex;

   Abstract : Faithful chromosome segregation at each cell division is essential as the formation of cells with an abnormal number of chromosomes (aneuploid cells) can result in infertility, developmental defects or cancer. Aneuploidy occurs in approximately 20% of all conceptions, causing infertility and embryo death. READ MORE