Search for dissertations about: "Saeedeh Mirzaee"

Found 1 swedish dissertation containing the words Saeedeh Mirzaee.

2. 1. The role of 5'-nucleotidases and deoxynucleoside kinases in responses to nucleoside analogues

   Author : Saeedeh Mirzaee; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The efficacy of nucleoside analogues (NAs) in treating several hematological malignancies, solid tumors and viral infections is limited primarily by side-effects and the development of drug resistance. The aims of the present thesis were to elucidate mechanism(s) involved in tissue-specific toxicity associated with NA therapy, as well as the mechanisms underlying resistance to these drugs. READ MORE