Search for dissertations about: "Sara Lind"

Showing result 1 - 5 of 7 swedish dissertations containing the words Sara Lind.

  2. 1. Innate mechanisms regulating B cell activation in inflammatory diseases

    Author : Sara Lind; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Generation of powerful and highly specific immune responses against invading pathogens is essential to our survival. However, the immune system can cause disease if activated in an inappropriate manner. READ MORE

  4. 2. Vitamin A and Osteoporosis : Experimental and Clinical Studies

    Author : Sara Johansson; Håkan Melhus; Andreas Kindmark; Monica Lind; Göran Toss; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; vitamin A; bone; osteoporosis; Invärtesmedicin; Internal medicine; Invärtesmedicin;

    Abstract : Vitamin A in high doses is severely toxic to the rat skeleton, and the active metabolite retinoic acid (RA) can induce bone resorption in vitro. An excessive dietary intake of vitamin A has been associated with reduced bone mineral density and an increased risk of hip fracture. READ MORE

  5. 3. Comorbidity, distress, coping and social support in asthma and allergy

    Author : Nina Lind; Steven Nordin; Anna-Sara Claeson; Eva Millqvist; Rosalind Wright; Umeå universitet; []
    Keywords : atopy; asthma; allergy; allergic rhinitis; atopic dermatitis; environmental intolerance; chemical intolerance; building intolerance; psychological distress; stress; anxiety; depression; burnout; coping; social support;

    Abstract : Asthma and allergies are some of the most common illnesses worldwide that almost everybody will come in contact with. This thesis studied persons with allergic asthma, non-allergic asthma, allergic rhinitis and atopic dermatitis in a population-based sample. At an early stage, these illnesses were regarded as psychosomatic. READ MORE

  6. 4. Development and evaluation of analytical techniques for antibodies and antibody-drug conjugates : From verification of conjugation to stability testing

    Author : Malin Källsten; Jonas Bergquist; Fredrik Lehmann; Sara Lind; Lucia Kovac; Alain Beck; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibody-drug conjugates; drug-to-antibody ratio; monoclonal antibody; mass spectrometry; hydrophobic interaction chromatography; sample preparation; aggregation; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Abstract : Antibody-drug conjugates (ADCs) are becoming increasingly important in oncology. ADCs are inherently heterogeneous analytes. For a successful drug candidate to go through to the clinic, extensive characterization and evaluation of the constructs are necessary. READ MORE

  7. 5. Proteomic Analysis of Urinary Bladder Cancer : Aiming for Novel Biomarkers

    Author : Mårten Lindén; Per-Uno Malmström; Ulrika Segersten; Sara Bergström Lind; Lars Egevad; Uppsala universitet; []
    Keywords : urine; APOE; FGB; GAL1; LRG1; POLR1E; SERPINA1; STMN1; TOP2A; biomarker; diagnostic biomarker; prognostic biomarker; predictive biomarker; mass spectrometry; western blot; dot blot; immunohistochemistry; IHC; tissue microarray; TMA; urothelium; antibody; antibody-based; urinblåsecancer; biomarkör; diagnos; prognos; urin; proteomik; masspektrometri; immunohistokemi; antikroppar; Molecular Biology; Molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Abstract : Urinary bladder cancer is a heterogeneous disease appearing in different forms, e.g. non-muscle invasive and muscle invasive. For all variants, the expression of proteins is interesting to analyze for diagnostic, predictive, prognostic and drug targeting purposes, since it reflects the altered gene expression causing the cancer. READ MORE