Search for dissertations about: "Satellite cells"

Showing result 16 - 20 of 44 swedish dissertations containing the words Satellite cells.

  2. 16. Contracting muscle for regeneration : myogenic dedifferentiation in limb progenitor cell formation

    Author : Sara Lööf; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The urodele amphibians, such as newts and axolotls, are unique among vertebrates since they regenerate their limbs, tail, jaws and part of their heart and CNS as adults. After amputation of a newt limb, regeneration proceeds by the reversal of differentiation of tissues in the limb stump. READ MORE

  4. 17. Expression and regulation of neuronal messenger molecules : focus on the NO-cGMP pathway and galanin in autonomic and sensory neurons

    Author : Kristina Holmberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : adrenal gland; autonomic ganglia; cGMP; dorsal root ganglion; galanin; immunohistochemistry; in situ hybridization; nerve growth factor; neuropeptides; nitric oxide synthase; sodium nitroprusside; transgenic mice;

    Abstract : The autonomic nervous system consists of the sympathetic, parasympathetic and enteric divisions. The sympathetic pre- and paravertebral neurons are in principle of noradrenergic phenotype. However, originally pharmacological experiments indicated that sympathetic fibers projecting to the sweat glands are cholinergic. READ MORE

  5. 18. Observations on morphology and function of cutaneous and subcutaneous sensory mechanoreceptors : an experimental study in mammals

    Author : Birgit Stark; Karolinska Institutet; Karolinska Institutet; []
    Keywords : mechanoreceptors; somatosensory organisation; blood-nerve barrier; Glucose transporter-1; nerve regeneration; TGF-ß family; neurotrophin receptors;

    Abstract : Tactile sensory discrimination is dependent upon an intact system of peripheral mechanoreceptors, their nerve fibre afferents with cell bodies in the dorsal root ganglion and the dorsal column-medial lemniscal system which relays tactile information from the skin to the cortex. Injury to any part of the afferent pathways leads to compromised mechanoreceptive perception. READ MORE

  6. 19. Role of latent EBV genes in the induction of genomic instability in Burkitt’s lymphoma

    Author : Bettina Gruhne; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Epidemiological and molecular evidence link Epstein-Barr virus (EBV) infection to a variety of lymphoid and epithelial malignancies but the contribution of the virus to tumorigenesis is unclear. Genomic instability, defined by the establishment of a mutator phenotype and characterized by the occurrence of non-clonal chromosomal aberrations, excessive DNA damage and defects in DNA repair, is the hallmark of malignant transformation. READ MORE

  7. 20. Energy metabolism as a target for new treatment strategies in Huntington’s disease

    Author : Marie Sjögren; Biomarkörer vid hjärnsjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington´s disease; Energy metabolic alteration; Weight loss; Skeletal muscle; Adipose tissue; R6 2; Ghrelin; Liraglutide;

    Abstract : Huntington´s disease (HD) is a fatal inherited neurodegenerative disorder caused by a CAG triplet repeat expansion in the huntingtin (HTT) gene and characterized by cognitive and motoric dysfunctions as well as psychiatric problems. Accumulating evidence, however, suggests altered energy metabolism and a hyper-catabolic state as key features of HD pathology. READ MORE