Search for dissertations about: "Satellite cells"

Showing result 21 - 25 of 44 swedish dissertations containing the words Satellite cells.

  2. 21. Magnetic Nanoparticle Based Biosensors for Pathogen Detection and Cancer Diagnostics

    Author : Bo Tian; Mattias Strömberg; Peter Svedlindh; Hakho Lee; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Magnetic biosensors; magnetic nanoparticles; homogeneous assays; volumetric sensing; Engineering Science with specialization in Solid State Physics; Teknisk fysik med inriktning mot fasta tillståndets fysik;

    Abstract : This thesis describes several magnetic nanoparticle (MNP)-based biosensing strategies which take advantage of different magnetic sensors, molecular tools and nanotechnologies. Proposed biosensors can be classified into three groups, i.e., immunoassay-based, molecular amplification-based, and nanoparticle assembly-based. READ MORE

  4. 22. The muscle cytoskeleton of mice and men : Structural remodelling in desmin myopathies

    Author : Lena Carlsson; Lars-Eric Thornell; Anders Arnér; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; desmin; nestin; synemin; paranemin; plectin; αB-crystallin; skeletal muscle; heart muscle; myotendinous junction; motor endplate; costamere; anatomi; Human Anatomy;

    Abstract : The muscle fibre cytoskeleton of skeletal and heart muscle cells is composed mainly of intermediate filaments (IFs), that surround the myofibrils and connect the peripheral myofibrils with the sarcolemma and the nuclear membrane. Desmin is the first muscle specific IF protein to be produced in developing muscles and is the main IF protein in mature muscles. READ MORE

  5. 23. Cellular and molecular mechanisms of inflammatory arthritis and fibromyalgia

    Author : Carlos Eduardo Morado Urbina; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In Study I, we examined the impact of the hR100E-NGF mutation on inflammatory pain and bone erosion in both female and male mice. Our findings indicate that the hR100E-NGF mutation did not affect the development of the peripheral sensory nervous system at the lumbar DRG, sciatic nerve, ankle joint, or glabrous skin. READ MORE

  6. 24. Chromosomal Instability and Genomic Amplification in Bone and Soft Tissue Tumours

    Author : David Gisselsson Nord; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nuclear atypia; kinetochore; anaphase bridge; p53; breakage-fusion-bridge cycle; TP53; HMGIC; MDM2; mitotic instability; genomic instability; FISH; osteosarcoma; liposarcoma; amplification; tumour; chromosome; cytogenetics; Clinical genetics; Klinisk genetik;

    Abstract : Acquired genetic abnormalities are found in all types of malignant tumours and may contribute to neoplastic processes by altering protein structure or dosage. Many bone and soft tissue tumours (BSTT) are characterised by complex patterns of chromosome changes, including extensive intratumour heterogeneity and amplification of DNA sequences. READ MORE

  7. 25. Crisis in Energy Metabolism - Mitochondrial Defects and a New Disease Entity

    Author : Gittan Kollberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Energy metabolism; Mitochondrial Disorders; mtDNA; multiple mtDNA deletions; Alpers-Huttenlocher syndrome; POLG1; GYS1; glycogen synthase; point mutation; Polymerase gamma;

    Abstract : Impairment of energy metabolism may be associated with severe implications for affected individuals since all fundamental cell functions are energy-dependent. Disorders of energy metabolism are often genetic and associated with defects in the oxidative phosphorylation in mitochondria. READ MORE