Search for dissertations about: "Schwann cell"

Showing result 1 - 5 of 52 swedish dissertations containing the words Schwann cell.

  2. 1. Regulation of Injury Induced Schwann Cell Proliferation Schwann Cell Proliferation

    Author : Åsa Fex Svenningsen; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; estrogen; signal transduction; insulin like growth-factors; Schwann cell; peripheral; nerve regeneration; Djurfysiologi; Animal physiology; progesterone;

    Abstract : The purpose of this study was to investigate injury induced proliferation of Schwann cells with emphasis of the effects of the insulin-like growth factors (IGF-I and IGF-II) and the sex hormones progesterone and estrogen. Proliferation, measured as [3H] thymidine incorporation, was studied in cultured segments of the rat sciatic nerve or through the use of the thymidine analogue bromo- deoxy-uridine (BrdU) in combination with immunocytochemistry. READ MORE

  4. 2. Neuromuscular injuries and pharyngeal dysfunction in snorers and sleep apnea patients : a study on pathological changes in the human soft palate and its relationship with swallowing dysfunction

    Author : Farhan Shah; Per Stål; Sture Forsgren; Diana Berggren; Eva Svanborg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Axons; BDNF; desmin; dystrophin; obstructive sleep apnea; OSA; pharyngeal function; muscle; myopathy; neuropathy; Schwann cells; swallowing dysfunction; upper airway; Medical Cell Biology; medicinsk cellbiologi; oto-rhino-laryngologi; Oto-Rhino-Laryngology; patologi; Pathology; molecular cell biology; molekylär cellbiologi;

    Abstract : Obstructive sleep apnea (OSA) is a prevalent progressive sleep disorder with serious negative health consequences. Although several risk factors such as obesity can make an individual vulnerable to develop OSA, the pathophysiological mechanism for the collapse of the upper airway is unclear. READ MORE

  5. 3. Neuron-glial Interaction in the Developing Peripheral Nervous System

    Author : Mikael Corell; Åsa Fex Svenningsen; Klas Kullander; Helgi Schöith; Heape Anthony; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Schwann cell; nonmyelinating Schwann cell; myelinating Schwann cell; development; proliferation; differentiation; myelin; neural stem cell; central nervous system; peripheral nervous system; enteric nervous system; N-cadherin; GABA; GAD; GABA B receptor; baclofen; CGP55485; Neuroscience; Neurovetenskap; Neuroscience; Neurovetenskap;

    Abstract : The nervous system, including the brain, is the most sophisticated organ in the mammalian body. In such a complex network, neuron-glial interaction is essential and controls most developmental processes, such as stem cell fate determination, migration, differentiation, synapse formation, ensheathment and myelination. READ MORE

  6. 4. Cell therapy for denervated tissue

    Author : Roine El-Habta; Ludvig J. Backman; Paul J. Kingham; Patrik Danielson; António Salgado; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue-derived stem cell; cell therapy; denervation; differentiation; myoblast; peripheral nerve injury; proliferation; regeneration; skeletal muscle; stromal vascular fraction; survival; tendon; cellforskning; cell research; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Background: Peripheral nerve injury results in denervation of tendons and muscles. The biology of denervated muscle has been well studied but little is known about the associated tendons. READ MORE

  7. 5. Development of biosynthetic conduits for peripheral nerve repair

    Author : Aleksandra McGrath; Liudmila N Novikova; John Haycock; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biosynthetic conduit; Mesenchymal stem cells; Nerve graft; Nerve tissue engineering; Peripheral nerve injury; Schwann cells;

    Abstract : Peripheral nerve injuries are often associated with significant loss of nervous tissue leading to poor restoration of function following repair of injured nerves. Although the injury gap could be bridged by autologous nerve graft, the limited access to donor material and additional morbidity such as loss of sensation and scarring have prompted a search for biosynthetic nerve transplants. READ MORE