Search for dissertations about: "Sebastian Braun"
Found 1 swedish dissertation containing the words Sebastian Braun.
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1. Downstream effects of master regulators in two brain diseases
Abstract : In paper one, we investigated how the pharmacological activation and inhibition of the glucocorticoid system affects lifespan and symptoms in a mouse model for RTT. We performed a long-term drug treatment study with the GR activator corticosterone and the GR inhibitor RU486 under which we measured the lifespan and onset of RTT-like symptoms of male Mecp2-null and female Mecp2 heterozygous mice in comparison to untreated mutant and to treated and untreated wild-type animals. READ MORE
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