Search for dissertations about: "Severer"

Found 5 swedish dissertations containing the word Severer.

2. 1. Role of cytokines in experimental neurodegenerative and neuroinflammatory disorders

   Author : Xing-Mei Zhang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Altered expression of cytokines in response to body injury has diverse actions that can exacerbate, mediate, reduce or inhibit neuronal and myelin damage as well as influence the disease development in a variety of nervous system disorders, such as Alzheimer s disease (AD), multiple sclerosis and Guillain-Barré Syndrome (GBS). In these studies, we attempted to explore the possible roles of tumor necrosis factor (TNF)-α and interleukin (IL)-18 in experimental neurodegenerative and neuroinflammatory disorders. READ MORE

4. 2. Adults with cystic fibrosis : mental health and patient experiences of the CF treatment

   Author : Lena Backström Eriksson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: Cystic fibrosis (CF) is an autosomal recessive inherited, life shortening multi organ disease most typically affecting the respiratory system and the gastrointestinal tract. In recent decades progresses in the management of CF has led to an increasing proportion of adults with CF. READ MORE

5. 3. Genetic epidemiological studies of the functional somatic syndromes : chronic widespread pain and chronic fatigue

   Author : Kenji Kato; Karolinska Institutet; Karolinska Institutet; []
   Keywords : functional somatic syndrome; chronic widespread pain; fibromyalgia; chronic fatigue; comorbidity; twins; genetic factors; environmental factors; sex differences; personality; stress;

   Abstract : Fibromyalgia and chronic fatigue syndrome are two symptom-defined conditions with many physical symptoms in common, such as muscle pain, fatigue, unrefreshing sleep, and impairment in memory or concentration. These two conditions often co-occur and frequently co-exist with other symptom-defined conditions (e.g. READ MORE

6. 4. Large cerebral artery occlusion and recanalisation in stroke patients treated with intravenous thrombolysis : clinical and radiological markers and their clinical relevance

   Author : Tatiana Kharitonova; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Large cerebral artery occlusion accounts for 40-46% of ischemic strokes. These strokes are characterized by extensive neurological deficit, poor functional outcome, and increased mortality (up to 40-80% in the most severe clinical syndromes). READ MORE

7. 5. Prevalence and impact of chronic diseases and multimorbidity in the aging population : a clinical and epidemiological approach

   Author : Alessandra Marengoni; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Chronic diseases; multimorbidity; comorbidity; education; occupation; disability; mortality;

   Abstract : Due to the aging of the population, the absolute number of subjects affected by age-related diseases is expected to increase as well as their coexistence known as multimorbidity.The aims of this thesis were to evaluate the prevalence, distribution and patterns of chronic multimorbidity in the elderly population, and its impact on disability, functional decline and mortality. READ MORE