Search for dissertations about: "Shigella"

Showing result 1 - 5 of 22 swedish dissertations containing the word Shigella.

  2. 1. Role of extracellular ATP in immune mechanisms against infections

    Author : Lalitha Tadala; Andrea Puhar; Sara I Wilson; Bernt Eric Uhlin; Mikael Sellin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular ATP; invasive bacteria; Shigella; Listeria; plasma membrane ruffle; PIEZO1; infection; immune response; Hanta virus; molekylär cellbiologi; molecular cell biology;

    Abstract : Inflammation is driven either by infection with pathogens or sterile stimuli, such as tissue damage or autoimmune diseases. Upon tissue damage, ATP is released passively from the dead or compromised cells. During stress, ATP can be secreted from the cells. Extracellular ATP (eATP) acts as an endogenous danger signal. READ MORE

  4. 2. Chemical studies of 0-antigens from Shigella

    Author : Kurt Petersson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The structure of 13 types of Shigella flexneri O-antigens has been determined, using a N-deacetylation-deamination reaction sequence. The correlation between chemical structures and immunological classification of Shigella flexneri is discussed. READ MORE

  5. 3. Characterization of Shigella dysenteriae type 1 hybrid vaccine candidates

    Author : Inger Fält; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Shigellae is endemic in many developing countries in the world and a major cause of childhood diarrheal morbidity and mortality. Infections caused by Shigella dysenteriae type 1 are particularly severe. READ MORE

  6. 4. Prediction of 3D structures of oligosaccharides. Methodological development and studies on saccharide antigens of interest for vaccine design

    Author : Jimmy Rosen; Göteborgs universitet; []
    Keywords : Oligosaccharide; conformation; 3D structure; O-antigen; Shigella dysenteriae; Escherichia coli; Burkholderia cepacia; Schistosoma mansoni; filtered systematic search; genetic algorithm;

    Abstract : This thesis presents 3D structure predictions of five immunologically active surfacepolysaccharides of pathogens, which are of interest as targets for development of glycoconjugatevaccines. Furthermore it describes two methods which have been used for theconformational predictionsThe Shigella dysenteriae type 2 Oantigenwas predicted to form a compact helicalstructure with three repeating pentasaccharide units per turn. READ MORE

  7. 5. Central line-associated bloodstream infection and application of high resolution melting to methicillin resistant Staphylococcus aureus and Shigella sonnei genotyping

    Author : Waleed Mazi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Effective infection prevention and control hospital program is essential for prevention hospital associated infections (HAIs). Central line-associated bloodstream infection (CLABSI) is one of the major threating patients in intensive care units (ICUs). READ MORE