Search for dissertations about: "Siamak Haghdoost"
Showing result 1 - 5 of 13 swedish dissertations containing the words Siamak Haghdoost.
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1. Biomarkers of oxidative stress and their application for assessment of individual radiosensitivity
Abstract : Radiotherapy is one of the most common therapeutic methods for treatment of many types of cancer. Despite many decades of development and experience there is much to improve, both in efficacy of treatment and to decrease the incidences of adverse healthy tissue reactions. READ MORE
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2. In vitro and in vivo aspects of intrinsic radiosensitivity
Abstract : This thesis focuses on how physical and biological factors influence the outcome of exposures to γ/X-rays. That the dose rate changes during real life exposure scenarios is well-known, but radiobiological data from exposures performed at increasing or decreasing dose rates is lacking. READ MORE
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3. Factors modifying cellular response to ionizing radiation
Abstract : Many physical factors influence the biological effect of exposure to ionizing radiation, including radiation quality, dose rate and temperature. This thesis focuses on how these factors influence the outcome of exposure and the mechanisms behind the cellular response. READ MORE
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4. The role of MTH1 in ultraviolet radiation-induced mutagenesis
Abstract : Ultraviolet radiation (UVR) is known to be highly mutagenic. What types of DNA lesions that are induced by different UVR wavelengths are still a matter of debate. UVR induces mutagenesis mostly by the formation of photoproducts and the induction of reactive oxygen species (ROS). READ MORE
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5. Oxidized nucleotides as a predictor of radiation sensitivity
Abstract : The direct and indirect effects of IR can lead to DNA damage and activation of DNA repair. The indirect effects of ionizing radiation mediated by reactive oxygen species (ROS) which produced through radiolysis of water and if not taken care of by the antioxidant system, can also give rise to oxidative stress. READ MORE