Search for dissertations about: "Small RNA"
Showing result 11 - 15 of 313 swedish dissertations containing the words Small RNA.
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11. Regulation of RNA Editing : The impact of inosine on the neuronal transcriptome
Abstract : The transcriptome of the mammalian brain is extensively modified by adenosine to inosine (A-to-I) nucleotide conversion by two adenosine deaminases (ADAR1 and ADAR2). As adenosine and inosine have different base pairing properties, A-to-I RNA editing shapes the functional output of both coding and non-coding RNAs (ncRNAs) in the brain. READ MORE
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12. Crystallographic studies of small RNA bacteriophages
Abstract : .... READ MORE
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13. Multifaceted RNA-mediated regulatory mechanisms in Streptococcus pyogenes
Abstract : Bacterial pathogens rely on precise regulation of gene expression to coordinate host infection processes and resist invasion by mobile genetic elements. An interconnected network of protein and RNA regulators dynamically controls the expression of virulence factors using a variety of mechanisms. READ MORE
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14. Nucleic Acids as Drug Targets -Interactions of Platinum Complexes, Polyamines, and siRNA with DNA and RNA Models
Abstract : Drugs targeting nucleic acids were studied in DNA and RNA model systems. The effects were investigated with respect to structural and thermodynamic influence, kinetics, and biological function. The drugs employed in this thesis were anticancer active platinum(II) complexes, polyamine derivatives, and siRNA. READ MORE
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15. Development and application of spatial transcriptomics methods
Abstract : Transcriptomics is one of the pivotal fields in molecular biology, enabling comprehensive analysis of gene expression patterns. Recent advancements in the biotechnology field have transformed the transcriptomics research, providing insights into the complexity of cellular processes in a greater detail. READ MORE