Search for dissertations about: "Soleus"

Showing result 1 - 5 of 45 swedish dissertations containing the word Soleus.

2. 1. Neuromuscular adaptations to muscle fatigue during submaximal isometric contractions in man

   Author : Wolfgang N Löscher; Karolinska Institutet; Karolinska Institutet; []
   Keywords : isometric; electromyography; tremor; H-reflex; twitch; motoneuron; recruitment; la-afferents; recurrent inhibition; central fatigue; excitatory drive; gastrocnemius; soleus; triceps surae; tendon vibration; ischemia; Renshaw cellStockholm 1995;

   Abstract : During a sustained contraction, the force producing capacity of a muscle gradually decreases. In order to maintain a constant force output, the neuromuscular system has to adapt to the contractile fatigue process. READ MORE

4. 2. Effects of ageing on contractility and myosin composition of rat and man skeletal muscles and muscle cells : with special reference to muscle adaptability

   Author : Xiaopeng Li; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ageing; hyperthyroidism; skeletal muscle; single skinned fibre; isometric twitch; slack test; shortening velociy; electrophoresis; myosin isoform; immunocytochemistry;

   Abstract : The aims of this thesis were to characterize the effects of ageing on the contractile and biochemical properties of fast- and slow-twitch skeletal muscles at the whole muscle and single fibre level in an attempt to improve our understanding of the mechanisms underlying the age-related impairments of muscle fibres. Specific interest was in the adaptability of skeletal muscle and the regulation of speed of shortening at single-cell level in the rat and man. READ MORE

5. 3. Structure and function of the cytoskeleton in cardiac and skeletal muscle

   Author : Johanna Balogh; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP-receptor; Cardiovascular system; Kardiovaskulära systemet; cardiomyopathy; transgenic mice; skeletal muscle; heart; muscle contraction; cytoskeleton; desmin;

   Abstract : We have examined the functional and structural roles of the cytoskeletal protein desmin in cardiac and skeletal muscles using a genetically modified mouse (Des-/-) with the desmin gene ablated. Desmin forms filaments at the Z-disks in the striated muscle sarcomere, have connections to the sarcolemma and most likely align sarcomeres and whole cells. READ MORE

6. 4. Mechanisms regulating metabolic and mitogenic events in skeletal muscle : implications for insulin resistance and exercise

   Author : Jeffrey W Ryder; Karolinska Institutet; Karolinska Institutet; []
   Keywords : skeletal muscle; glucose transport; GLUT4; hypoxia; exercise; Type II diabetes; MAPK; PPAR[gamma] thiazolidinediones;

   Abstract : Reduced glucose transport in skeletal muscle is a hallmark feature of Type II diabetes. Numerous mechanisms acutely or chronically regulate skeletal muscle glucose transport. The role of GLUT4, mitogen-activated protein kinases (MAPK), and peroxisome proliferator-activated receptor [gamma] (PPAR[gamma]) were examined in skeletal muscle. READ MORE

7. 5. Adaptability of skeletal muscle to hormone treatment in relation to gender and aging

   Author : Fushun Yu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : skinned muscle fiber; gender; aging; steroid hormone; V0 electrophoresis; MyHC; MyLC; enzymehistochemistry; hyperthyroid rat; thyroid hormone receptor TR deficient TR[alpha]1 - -; TR[beta]- -; and TR[alpha]1- -[beta]- - mice;

   Abstract : The aims of this study were to investigate the expression of myosin isoforms, muscle contractility at the cell level, and changes in these parameters in response to altered hormonal status in aging male and female rodents. In addition, by using mice lacking thyroid hormone receptors (TR[alpha]1 or TR[beta] or TR[alpha]1/[beta]) we tried to improve our understanding of the mechanisms by which thyroid hormone regulates the expression of specific MyHC isoforms via these different nuclear receptors. READ MORE