Search for dissertations about: "Sprague-Dawley rat"

Showing result 1 - 5 of 49 swedish dissertations containing the words Sprague-Dawley rat.

  1. 1. Time-related Aspects of Otoprotection : Experimental Studies in Rat

    Author : Adnan Lidian; Matti Anniko; Petri Olivius; Uppsala universitet; []
    Keywords : sensorineural hearing loss; Edaravone; brain-derived neurotrophic factor; auditory brainstem response; Sprague-Dawley rat; distortion product otoacoustic emission; Pseudomonas aeruginosa exotoxin A.; Oto-Rhino-Laryngology; Oto-rhino-laryngologi;

    Abstract : Intratympanic injection of various otoprotectants through the round window membrane (RWM) might become available in the near future as an alternative to the currently available medical and surgical methods used to treat several inner ear diseases. The most common outcome of such diseases is sensorineural hearing loss (SNHL). READ MORE

  2. 2. Parietal cell regeneration in rat gastric mucosal wounds : a quantitative light and electron microscopical study

    Author : Håkan Blom; Herbert Helander; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rat; gastric mucosa; gastric wounds; parietal cells; re­generation; pyloroplasty; truncal vagotomy; antrectomy; pen­tagastrin; cimetidine; carbacholine; stereology; light microscopy; electron microscopy; pH-studies;

    Abstract : The aims of the study were to obtain a method with which it would be possible to produce standardized wounds in the gastric mucosa, and to follow the regeneration of the acid producing parietal cells in those lesions during different experimental conditions. Quantitative methods applied to light and electron microscopy were used. READ MORE

  3. 3. Immunological and Inflammtory Responses against Intrastriatal Neural Grafts in the Rat

    Author : Wei-Ming Duan; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; MHC; Rat; Brain; Xenogeneic; Allogeneic; Syngeneic; Cytokine; Inflammation; Neural transplantation; Immunology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Abstract : Intracerebral neural transplantation offers a new strategy to combat Parkinson’s and Huntington’s diseases. However, a host immune response against a histoincompatible neural graft in the brain may jeopardize transplant survival. READ MORE

  4. 4. Computerised Microtomography : Non-invasive imaging and analysis of biological samples, with special reference to monitoring development of osteoporosis in small animals

    Author : Mats Stenström; Gudrun Alm Carlsson; Carl Carlsson; Jim Elliot; Linköpings universitet; []
    Keywords : Computed microtomography; CμT; signal-to-noise ratio SNR ; non-invasive monitoring; morphological changes; Gastrectomized Sprague-Dawley; osteoporosis; MEDICINE; MEDICIN;

    Abstract : The use of Computerised microtomography (CμT) in biomedical research is well established, with most applications developed at synchrotron facilities. The possibility to non-invasively monitor morphological changes in biological samples, makes it an attractive technique in biomedicine. READ MORE

  5. 5. Anabolic androgenic steroids and central monoaminergic systems : Supratherapeutic doses of nandrolone decanoate affect dopamine and serotonin

    Author : Carolina Birgner; Lena Bergström; Anna Kindlundh-Högberg; Fred Nyberg; Stefan Brené; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; anabolic androgenic steroids; nandrolone decanoate; dopamine; serotonin; rat; central nervous system; Pharmacology; Farmakologi;

    Abstract : Supratherapeutic doses of anabolic androgenic steroids (AASs) are administered, not only as performance-enhancing drugs in the world of sports, but also in order to modify behaviour. AAS abusers are at risk of developing serious physical and psychological side effects such as dependence and aggressive behaviour. READ MORE