Search for dissertations about: "Stroke Volume and outcome"

Showing result 1 - 5 of 14 swedish dissertations containing the words Stroke Volume and outcome.

2. 1. Ischemic Stroke Outcomes - Analyses of Protein and Genetic Biomarkers

   Author : Annie Pedersen; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; Prognosis; Biomarkers; Genetics; Genome-Wide Association Study;

   Abstract : The overall aim of this thesis was to identify novel biomarkers for ischemic stroke outcomes. The specific aims were to test the hypotheses that circulating concentrations of hemostatic biomarkers predict the long-term post-stroke risk of recurrent vascular events/death (paper I) and/or cognitive impairment (paper II) and that circulating concentrations of a marker of neuronal damage (neurofilament light chain, NfL) predict post-stroke functional and neurological outcomes (paper III) as well as to identify genetic variants associated with post-stroke functional outcome through a genome wide association study (GWAS) approach (paper IV). READ MORE

4. 2. Mitral Valve Surgery: Effects on Cardiac Reverse Remodeling, Hemodynamics, and Clinical Outcome

   Author : Snejana Hyllen; Thoraxkirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cardiac function; mitral regurgitation; myocardial remodeling; mitral valve repair;

   Abstract : Normalization of life expectancy after mitral valve surgery is highly dependent on early diagnosis and referral for surgical treatment. Among cases treated surgically, the majority (60–70%) have a degenerative etiology, which is also easiest to repair. READ MORE

5. 3. Experimental Traumatic Brain Injury and Cell Death - in vivo and in vitro aspects

   Author : Gustav Mattiasson; Sektion IV; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsychology; Neurology; uncoupling protein; mitochondrial permeability transition; cerebral blood flow; functional outcome; cell death; mitochondria; hippocampus; preconditioning; trauma; Brain; ischemia; neuropsykologi; Neurologi; neurophysiology;

   Abstract : Traumatic and ischemic brain damage are major causes of disability and death. While much effort has been spent on developing pharmacological treatments for these conditions, no neuroprotective drugs are in clinical use. READ MORE

6. 4. Pump Physiology in the Remodeled Heart

   Author : Björn Östenson; Lund Klinisk fysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac magnetic resonance; cardiac remodeling; exercise imaging; exercise physiology; regional contributions to stroke volume; feature-tracking strain; atrioventricular plane displacement; atrioventricular coupling; ventricular-arterial coupling; clinical physiology;

   Abstract : This thesis aimed to increase the understanding of pump physiology in the remodeled heart compared to normal pump physiology.Study I was a cross-sectional observatory study investigating the regional contributions to stroke volume in patients with heart failure prior to cardiac resynchronization therapy (CRT) and tested the hypothesis that this characterization of pumping could predict CRT response. READ MORE

7. 5. Cannabinoids as neuroprotective agents : a mechanistic study

   Author : Olov Nilsson; Christopher Fowler; Edward Högestätt; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cannabinoid; neuroprotection; inflammation; cytokine; neutrophil; Pharmacology; Farmakologi;

   Abstract : Glucose and oxygen supply to the brain is critical for its proper function and when it is restricted as during a stroke, neurons and glial cells quickly become necrotic leading to structural damage as well as functional impairment and even death. To date there are few effective therapies that inhibit the neurodegenerative process and improves the outcome for the affected individual. READ MORE