Search for dissertations about: "Subcellular organelles"
Showing result 1 - 5 of 20 swedish dissertations containing the words Subcellular organelles.
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1. Antibody-based subcellular localization of the human proteome
Abstract : This thesis describes the use of antibodies and immunofluorescence for subcellular localization of proteins. The key objective is the creation of an open-source atlas with information on the subcellular location of every human protein. READ MORE
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2. Membrane Proteins in Human Neutrophils - Identification and Characterization of Lipid Rafts in Subcellular Organelles
Abstract : The human neutrophil is an important effector cell in acute inflammation and in the innate immune response against bacteria and fungi. When immune reactions occur in the tissue in response to antigen challenge, neutrophils are the first cells to enter the site of inflammation. READ MORE
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3. Towards subcellular localization of the human proteome using bioimaging
Abstract : Since the publication of the complete sequence of the human genome in 2003 there has been great interest in exploring the functions of the proteins encoded by the genes. To reveal the function of each and every protein, investigation of protein localization at the subcellular level has become a central focus in this research area, since the localization and function of a protein is closely related. READ MORE
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4. The function of annexin I in human neutrophils. Studies of membrane binding
Abstract : The neutrophil granulocyte plays an important role in host defense against infections induced by invading microorganisms. The defense mechanism is dependent on the migration of neutrophils from the blood stream to the infected area, where the intruder is phagocytosed and killed. READ MORE
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5. Spatial proteome profiling of the compartments of the human cell using an antibody-based approach
Abstract : The human cell is complex, with countless processes ongoing in parallel in specialized compartments, the organelles. Cells can be studied in vitro by using immortalized cell lines that represent cells in vivo to a varying degree. READ MORE