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Found 5 swedish dissertations matching the above criteria.

2. 1. Nanoplasmonic Biosensing - Exploring Unique Possibilities

   Author : Magnus Jonsson; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; biosensor; nanoholes; nanopores; nanofabrication; localized surface plasmon resonance; quartz crystal microbalance; nanoplasmonics; structural sensing; artificial cell membrane;

   Abstract : Bioanalytical sensors are indispensible tools in medical diagnostics and drug discovery as well as for life science research, environmental monitoring and food safety. In essence, they are used to detect and determine the concentrations of specific biomolecules in complex mixtures. READ MORE

4. 2. Photoluminescence-based characterization of bioengineered nanovesicles and erbium emitters

   Author : Maryam Sanaee; Katia Gallo; Jerker Widengren; Martin Hof; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioengineered nanovesicles; Coincident fluorescent burst analysis; Drug loading; Erbium emitters; Lithium niobate; Photoluminescence.; Bioingenjörskonstruerade nanovesiklar; Analys av sammanfallande fluorescerande blossteknik; Läkemedelslastning; Erbium-emitterare; Lithium niobate; Fotoluminiscens.; Biologisk fysik; Biological Physics; Optics and Photonics; Optik och fotonik;

   Abstract : In recent decades, photoluminescence properties of single molecules and ions have opened new possibilities for studies on smaller size scales, below the light-diffraction limit. In this thesis, the advantages of such single photon emitters were harnessed and studied mainly in the field of biophysics, but also, in investigations within solid state photonics. READ MORE

5. 3. High-resolution Imaging of Cleared and Expanded Kidney Tissue Samples

   Author : David Unnersjö Jess; Hans Blom; Hjalmar Brismar; Lena Scott; Karlhans Endlich; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Kidney; Renal Pathology; Microscopy; Super-resolution microscopy; Tissue expansion; Foot processes; Glomerular filtration; Podocytes; Biological Physics; Biologisk fysik;

   Abstract : The kidney is one of the most important and complex organs in the humanbody with the task of filtering hundreds of litres of blood daily. It is responsiblefor the salt and acid/base balance in the body, as well as secretinghormones important for red blood cell production and blood pressure regulation. READ MORE

6. 4. Creating cell microenvironments in vitro

   Author : Patric Wallin; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell migration; lipid bilayers; cell differentiation; liquid handling; surface functionalization; Microfluidics; chemotractant gradients; mammalian cell culture; cell microenvironments; in vitro screening assay;

   Abstract : Stem cells have a great potential to bring about advancements in fields like developmental biology, drug discovery, cancer biology and tissue engineering. In order to be able to use stem cells to their full potential, it is important to have control over their behavior. READ MORE

7. 5. Fragment-based drug discovery : Novel methods and strategies for identifying and evolving fragment leads

   Author : Edward A. FitzGerald; Helena Danielson; Hanna-Kirsti Schrøder Leiros; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Drug Discovery; Biophysics; Fragment-based drug discovery; Epigenetics; Biosensors; Surface Plasmon Resonance; Interaction Analysis; Second-Harmonics; Biokemi; Biochemistry;

   Abstract : The need for new drugs became ever more apparent in the year 2020 when the world was faced with a viral pandemic. How drugs are discovered and their relevance to society became part of daily discussions in workplaces and homes throughout the world. Consequently, efficient strategies for preclinical drug discovery are clearly needed. READ MORE