Search for dissertations about: "TET1"

Found 3 swedish dissertations containing the word TET1.

  1. 1. Studies of epigenetic deregulation in parathyroid tumors and small intestinal neuroendocrine tumors

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Elham Barazeghi; Uppsala universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epigenetics; 5hmC; TET1; TET2; parathyroid tumors; SI-NET; RRBS; PTPRM;

    Abstract : Deregulation of the epigenome is associated with the initiation and progression of various types of human cancers. Here we investigated the level of 5-hydroxymethylcytosine (5hmC), expression and function of TET1 and TET2, and DNA methylation in parathyroid tumors and small intestinal neuroendocrine tumors (SI-NETs). READ MORE

  2. 2. Novel mechanisms in depression: focus on telomere biology and epigenetic regulation

    University dissertation from Stockholm : Karolinska Institutet, Dept of Molecular Medicine and Surgery

    Author : Yabin Wei; Karolinska Institutet.; Karolinska Institutet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Telomere length;

    Abstract : Depression is a complex disorder with an average lifetime prevalence from 11.1% to 14.6%. It causes serious disability and is a significant public health problem worldwide. READ MORE

  3. 3. Alterations in proliferation and differentiation of neural stem cells induced by adverse neurodevelopmental factors

    University dissertation from Stockholm : Karolinska Institutet, Dept of Neuroscience

    Author : Raj Kumar Bose; Karolinska Institutet.; Karolinska Institutet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Predisposition to diseases can be acquired during early stages of development and resolve into an actual disorder later in life. Early life programming defines the association between challenges during pregnancy that result in altered fetal growth, and developmental and adult disorders. READ MORE