Search for dissertations about: "TLR POLYMORPHISM"

Found 2 swedish dissertations containing the words TLR POLYMORPHISM.

  2. 1. Tissue Factor and CD40 Ligand : Markers for the Interplay of Coagulation and Inflammation in the Acute Coronary Syndrome

    Author : Anders Mälarstig; Agneta Siegbahn; Lars Wallentin; Taavo Tenno; Fiona Green; Uppsala universitet; []
    Keywords : Molecular medicine; tissue factor; CD40 ligand; gene expression; single nucleotide polymorphism; acute coronary syndrome; myocardial infarction; coagulation; inflammation; Molekylärmedicin;

    Abstract : BACKGROUND: Tissue factor (TF) is a 47 kDa transmembrane glycoprotein known as the main initiator of blood coagulation. CD40 ligand is another membrane molecule, which ligates to cell types associated with atherosclerotic plaques thereby mediating intraplaque inflammation and weakening of the fibrous cap. READ MORE

  4. 2. A study on the role of genes of innate immunity in type 1 diabetes

    Author : Saikiran K Sedimbi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin-producing pancreatic beta-cells. It is a polygenic disease in which maximal genetic susceptibility is conferred by the presence of MHC class II genes. READ MORE