Search for dissertations about: "TP73"

Found 3 swedish dissertations containing the word TP73.

2. 1. Genetic alterations in Scandinavian neuroblastoma tumors

   Author : Katarina Ejeskär; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; loss of heterozygozity; deletion; 1p; 3p; CDC2L1; TP73; CORT; FHIT;

   Abstract : The results presented here derive from our efforts to find genes and chromosomal regions of interest in the formation and progression of the childhood tumor neuroblastoma.Neuroblastoma is the most common extracranial solid tumor of childhood. READ MORE

4. 2. Exploring the role of p73-isoforms during tumor development

   Author : Habib Abdullah Mohammad Sakil; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The p73 gene was first discovered in 1997 as a family member of p53, and since then this gene has been studied extensively in cancer biology. Among its two main classes of isoforms, TAp73 acts as a tumor suppressor, while in contrast ΔNp73 was shown to act in a dominant negative fashion as an oncogene which opposes the functions of TAp73 and p53. READ MORE

5. 3. Further delineation of molecular alterations in adreno-medullary tumors

   Author : Janos Geli; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Pheochromocytoma; abdominal paraganglioma; neuroblastoma; tumor suppressor gene; DNA methylation; gene expression; RIZ1; NORE1A; RASSF1A; CDKN2A;

   Abstract : Pheochromocytomas, abdominal paragangliomas and neuroblastomas are tumors of the sympathetic nervous system. Anatomically pheochromocytomas and abdominal paragangliomas arise from sympathoadrenal paraganglia, within and outside the adrenal medulla, respectively. READ MORE