Search for dissertations about: "TSG"

Showing result 1 - 5 of 16 swedish dissertations containing the word TSG.

  2. 1. Epigenetics in nasopharyngeal carcinoma

    Author : Di Sun; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NPC; Methylation; TSG; EBV; LMP1; CDH13; RASSF2A; MMSP;

    Abstract : Nasopharyngeal carcinoma (NPC) shows a remarkably distinctive ethnic and geographic distribution among the world suggesting that genetic susceptibility backgrounds cooperate with the environmental risk factors in etiology of NPCs. Among the environmental factors, much attention has been focused on a well-documented association with Epstein-Barr virus (EBV), which can be detected in 100% undifferentiated NPCs. READ MORE

  4. 2. Development of new approaches for tumor suppressor genes identification

    Author : Jinfeng Li; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Tumor suppressor gene TSG ; Cloning of deleted sequences CODE ; Cloning of polymorphisms COP ; Cloning of identical sequences CIS ; Gene inactivation test GIT .;

    Abstract : Development of tumor is a complex process involving multiple steps. New technologies for cloning and identifying genes playing critical role in cancer development are necessary. That is why we have focused our research on development of these approaches. READ MORE

  5. 3. DNA methylation and gene expression patterns in adrenal medullary tumors

    Author : Nimrod G B Kiss; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pheochromocytomas and abdominal paragangliomas are neuroendocrine tumors of the autonomous nervous system, arising in adrenal medulla and sympathetic ganglia throughout the abdomen. These tumors originate from catecholamine-producing chromaffin cells. Neuroblastomas are common childhood tumors in the adrenal medulla and abdominal ganglia. READ MORE

  6. 4. Genetic studies of neuroblastoma with emphasis on the apoptotic pathway

    Author : Frida Abel; Göteborgs universitet; []
    Keywords : child; cancer; neuroectodermal; neural crest; loss of heterozygosity; LOH; bcl-2; mcl-1; apaf-1; caspase-2; caspase-3; caspase-9; PIN; DLC-1; caspase-2;

    Abstract : Aim: The objective of this thesis was to find genes and chromosomal regions involved in neuroblastoma (NB) tumor progression. NB is a childhood tumor of the sympathetic nervous system that generally occurs spontaneously. READ MORE

  7. 5. Identification of tumor suppressor genes using the approach of gene inactivation test

    Author : Fuli Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Epithelial cancers are the most prevalent and lethal diseases in the world. They cause more than 80% of all cancer deaths. Development of these tumors is a complex process involving more than 100 genes from different chromosomes. We know that human chromosome 3 (chr. READ MORE