Search for dissertations about: "Tetramer"

Showing result 1 - 5 of 58 swedish dissertations containing the word Tetramer.

  2. 1. Cellular Immune Responses to Allografts and Cytomegalovirus

    Author : Mats Engstrand; Olle Korsgren; Gunnar Tufveson; Nils Persson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Transplantation; Rejection; Monitoring; Flow Cytometry; MHC; Tetramer; CMV; infection; Immunologi; Immunology; Immunologi;

    Abstract : Today the immunosuppressive treatment is kept to a level were the incidence of acute rejection is below 20% within the first year after transplantation. As a consequence, a group of transplanted patients is over-immunosuppressed and at risk for infections. READ MORE

  4. 2. Endonuclease II - a GIY-YIG enzyme of bacteriophage T4

    Author : Pernilla Lagerbäck; Karin Carlson; Elisabeth Raleigh; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; GIY-YIG; EndoII; endonuclease; structure; tetramer; binding; nicking; recombination; Microbiology; Mikrobiologi;

    Abstract : Endonuclease II (EndoII) of bacteriophage T4 is a GIY-YIG enzyme involved in host DNA breakdown during phage infection of E. coli. EndoII combines features of restriction endonucleases with those of homing endonucleases in that it breaks down DNA foreign to itself but recognizes a 16 bp long asymmetric and ambiguous sequence. READ MORE

  5. 3. Adoptive T Cell Therapy of Viral Infection and Cancer : Ex vivo Expansion of Cytomegalovirus- and Prostate Antigen-specific T Cells

    Author : Björn Carlsson; Magnus Essand; Thomas Tötterman; Malcolm Brenner; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunotherapy; Adoptive T cell therapy; Dendritic cell; T cell; Tetramer; Cytomegalovirus; Transplantation; pp65; Prostate cancer; TARP; Prostate antigens; Immunologi; Immunology; Immunologi;

    Abstract : The main focus of my thesis has been to develop protocols for generating antigen-specific cytotoxic T lymphocytes (CTLs) and T helper cells (TH) for adoptive transfer to treat cytomegalovirus (CMV) disease and prostate cancer. CMV viremia is a severe complication in immunocompromised stem cell transplanted patients. READ MORE

  6. 4. Cytomegalovirus Infection in Immunocompetent and Renal Transplant Patients : Clinical Aspects and T-cell Specific Immunity

    Author : Fredrik Sund; Britt-Marie Eriksson; Olle Korsgren; Halvor Rollag; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytomegalovirus; renal transplantation; cellular immunity; valacyclovir; mismatched; prophylaxis; tetramer; CD4 T cells; CD8 T cells; Infectious diseases; Infektionssjukdomar;

    Abstract : Cytomegalovirus (CMV) is a β-herpesvirus that, after primary infection, establishes a life-long persistence in the human host. Up to 90% of humans are infected with CMV, that is kept under control by CMV-specific CD8+ and CD4+ T cells. In patients with an impaired cellular immunity, however, CMV infections can be life-threatening. READ MORE

  7. 5. Engineering and Functionalization of Hemicellulose Hydrogels

    Author : Weifeng Zhao; Karin Odelius; Ann-Christine Albertsson; Ulrica Edlund; Tina Vermonden; KTH; []
    Keywords : Hemicellulose; O-acetyl-galactoglucomannan; hydrogels; stimuli-responsive; aniline tetramer; aniline pentamer; electro-active; conductivity; pH-sensitivity; magnetic field-responsive; micro-gels; swelling; drug delivery.; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Abstract : Hemicellulose is the second most abundant component in wood and is an important renewable resource  that is used in films, paper composites and biofuels.  Hemicelluloses  have  several  advantages,  including  their abundance,  degradability  and  renewability. READ MORE