Search for dissertations about: "Thioredoxin biosynthesis"

Found 5 swedish dissertations containing the words Thioredoxin biosynthesis.

  1. 1. In vitro studies on the biosynthesis and reduction of ubiquinone

    Author : Tomas Nordman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : The mevalonate pathway; Ubiquinone; Ubiquinol; Lipoamide dehydrogenase; Thioredoxin reductase; Glutathione reductase; Selenium;

    Abstract : This thesis concerns the role of ubiquinone, the only endogenously synthesised lipid soluble antioxidant, in the cellular defence against peroxidation of proteins and lipids. The aims of the present investigations were to study the biosynthesis of ubiquinone in two different organelle fractions, i.e. READ MORE

  2. 2. Biosynthesis and biological role of leukotrienes in human lymphocytes

    Author : Yilmaz Mahshid; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Leukotrienes (LT) are biologically active metabolites of arachidonic acid. The key enzyme in leukotriene biosynthesis is 5-lipoxygenase (5-LO). Leukotriene B4 exerts its biological effect mainly via BLT1, the high affinity receptor for LTB4. Leukotriene B4 is a potent proinflammatory and chemotactic mediator. READ MORE

  3. 3. Protein complexes in chlorophyll biosynthetic enzymes

    Author : Ragna Peterson Wulff; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; electron microscopy; mass spectrometry; Rhodobacter capsulatus; barley; cyclase; magnesium chelatase; chlorophyll biosynthetic pathway; Protein complex;

    Abstract : Proteins are found on the inside, in the membrane, on the surface and on the outside of cells. They form complicated structures and they interact with other molecules and proteins. READ MORE

  4. 4. Isoforms of mammalian glutaredoxin 2

    Author : Christoph Hudemann; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Iron-sulfur proteins are characterized by the presence of iron-sulfur clusters containing sulfide linked iron centers in variable oxidation states. Glutaredoxins (Grx) are, among other redoxins, increasingly recognized to be involved at the interface between redox regulation, iron metabolism and iron-cluster biosynthesis. READ MORE

  5. 5. Pleiotropic effects of HMG-CoA reductase inhibitors : studies in vitro and in vivo

    Author : Cristine Skogastierna; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiovascular disease (CVD) is the prime cause of death in industrialized countries, resulting from the progression of atherosclerotic lesions. An increased level of plasma cholesterol, particularly within low-density lipoproteins, is a principle risk factor, but also elevated triglycerides and low levels of high-density lipoprotein cholesterol. READ MORE