Search for dissertations about: "Thomas Walz"

Found 5 swedish dissertations containing the words Thomas Walz.

  2. 1. Transforming growth factor a in human hematopoietic cells

    Author : Thomas M. Walz; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : TGF-a, transforming growth factor a, is a potent growth factor belonging to the family of EGF (epidermal growth factor) -related proteins. Binding to the same receptor as EGF it has a ubiquitous repertoire of target cells, including, mesenchymal, epithelial and neuronal cells. READ MORE

  4. 2. Studies on the effect of ErbB tyrosine kinase inhibitors on malignant melanoma growth and survival in vitro

    Author : Emelie Djerf; Thomas Walz; Anna-Lotta Hallbeck; Olle Stål; Curt Peterson; Johan Hansson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Malignant melanoma has one of the fastest increasing incidences among the different types of cancerin the Western world. This raise can partly be ascribed to the change in sun habits that has takenplace during the last decades, since the major external risk factor for melanoma is exposure toultraviolet radiation. READ MORE

  5. 3. Studies of transforming growth factor alpha in normal and abnormal growth

    Author : Anna-Lotta Hallbeck; Åke Wasteson; Thomas Walz; Annelie Lindström; Carl-Henric Heldin; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TGF-alpha; HER; EGFR; synovia; synovial sarcoma; RA; synovitis; Medical cell biology; Medicinsk cellbiologi;

    Abstract : Regulation of growth is of fundamental importance for development of the organism and to maintain health. The induction of cell proliferation and matrix production are influenced by several different signaling systems, most importantly by growth factors. READ MORE

  6. 4. Experimental studies on ErbB targeted therapy in malignant melanoma

    Author : Emelie Severinsson; Thomas Walz; Anna-Lotta Hallbeck; Olle Stål; Olle Larsson; Linköpings universitet; []
    Keywords : ;

    Abstract : Malignant melanoma has one of the fastest increasing incidences among the different types of cancer in the Western world. This raise can partly be ascribed to the change in sun habits that has taken place during the last decades, since the major external risk factor for melanoma is exposure to ultraviolet radiation. READ MORE

  7. 5. Canertinib-induced leukemia cell death signaling : effects of a pan-ERBB inhibitor

    Author : Cecilia Trinks; Thomas Walz; Jan-Ingvar Jönsson; Anna-Lotta Hallbeck; Dan Grandér; Linköpings universitet; []
    Keywords : ;

    Abstract : Acute myelogenous leukemia (AML) is the most common acute leukemia affecting adults, the second most frequent leukemia in children, and remains one of the most difficult to cure. Despite a substantial progress in understanding the pathogenesis of AML, general and rather unspecific cytostatic drugs such as cytarabine and anthracyclins still make up the cornerstones of therapy. READ MORE