Search for dissertations about: "Tobias Elgán"

Found 1 swedish dissertation containing the words Tobias Elgán.

2. 1. Structure-function studies of glutaredoxins and related oxidoreductases

   Author : Tobias Elgán; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Thiol-disulfide oxidoreductase; thioredoxin; Trx; glutaredoxin; Grx; protein disulfide oxidoreductase; PDO; -C-X-X-C-; specificity; conformational stability; ligandinduced stability; CD spectroscopy; redox potential;

   Abstract : The members of the ubiquitous group of thiol-disulfide oxidoreductases are characterized by a conserved tertiary structure, the thioredoxin (Trx) fold, and by having a consensus -C-X-X-C- active site sequence motif. By utilizing the active site cysteines, these proteins participate in redox reactions by catalyzing reversible disulfide oxidation and reduction. READ MORE