Search for dissertations about: "Toll like receptor"

Showing result 1 - 5 of 107 swedish dissertations containing the words Toll like receptor.

  2. 1. Toll-like receptors (TLRs) and inflammatory bone modeling

    Author : Ali Kassem; Ulf Lerner; Pernilla Lundberg; Pedro Souza; Timothy Arnett; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toll-like receptor; osteoclast; osteoblast; bone resorption; bone formation; P. gingivalis; S. aureus; flagellin.;

    Abstract : Patients with inflammatory or infectious conditions such as periodontitis, peri-implantitis, osteomyelitis, rheumatoid arthritis, septic arthritis and loosened joint prosthesis display varying severity of destruction in the adjacent bone tissue. Bone loss in inflammatory diseases is considered a consequence of cytokine induced RANKL and subsequent enhanced osteoclast formation. READ MORE

  4. 2. Developing brain and systemic inflammation: a "Toll-like" link with consequences

    Author : Amin Mottahedin; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; developing brain; neonatal brain injury; hypoxia-ischemia; inflammation; infection; Toll-like receptor; choroid plexus; neuroimmunology; Mitochondria;

    Abstract : The developing brain is vulnerable to external insults, and perinatal brain injury (PBI) is a major cause of life-long neurological syndromes such as cerebral palsy. Currently, no pharmaceutical intervention is available. Hypoxia/ischemia (HI), infections and inflammation are implicated in the pathogenesis of PBI. READ MORE

  5. 3. Toll-like receptor activation induced changes in dendritic cells

    Author : Oscar Hammarfjord; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Dendritic cells (DC) are professional antigen-presenting cells that act as a “bridge” between innate and adaptive immunity by the induction and subsequent orchestration of immune responses. The ligation of Toll-like receptors (TLR) and other innate receptors on DC determines their immune-stimulating capacity. READ MORE

  6. 4. Role of Toll-like receptors in airway inflammation

    Author : Anne Månsson; Klinisk och experimentell allergiforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lymphocytes; peripheral blood; allergic rhinitis; tonsils; eosinophils; specific allergen immunotherapy;

    Abstract : Toll-like receptors (TLRs) are germline-encoded pathogen-recognition receptors that detect different microbial structures and activate the immune system. The human TLR family presently comprises ten members (TLR1-TLR10), each with distinct properties. READ MORE

  7. 5. Airway hyperresponsiveness and viral recognizing toll-like receptors

    Author : Magnus Starkhammar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Common colds caused by viruses are, in healthy individuals, usually self-limited and with relatively mild symptoms. In asthmatic individuals, respiratory viruses can burst the defense immune system and trigger asthma exacerbations, including causing airway hyperresponsiveness (AHR). READ MORE