Search for dissertations about: "Transcription"

Showing result 1 - 5 of 1955 swedish dissertations containing the word Transcription.

  2. 1. Regulation of immunoglobulin transcription

    Author : David Liberg; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; N-substituted benzamides; NFkB; transcription; B cells; immunoglobulin; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : Each Ig V-region has its own upstream promoter and the promoter of a mature Ig gene is thereby selected during the V(D)J recombination process. Upon comparison, it is evident that only one transcription factor binding site, the octamer, is preserved within all promoters. READ MORE

  4. 2. From Single Gene to Whole Genome Studies of Human Transcription Regulation

    Author : Alvaro Rada-Iglesias; Claes Wadelius; Henk Stunnenberg; Uppsala universitet; []
    Keywords : Genetics; transcription; ChIP-chip; genome-wide; transcription factors; in vivo; Genetik;

    Abstract : Transcriptional regulation largely determines which proteins and the protein levels that are found in a cell, and this is crucial in development, differentiation and responses to environmental stimuli. The major effectors of transcriptional regulation are a group of proteins known as transcription factors, which importance is supported by their frequent involvement in mendelian and complex diseases. READ MORE

  5. 3. Regulators of chromatin and transcription in Drosophila

    Author : Filip Crona; Mattias Mannervik; Fernando Azorin; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Transcription; chromatin; co-regulators; CBP; lysine demethylase; KDM4A; Brakeless; Drosophila; utvecklingsbiologi; Developmental Biology;

    Abstract : Development of multicellular organisms is achieved by organized temporal and spatial patterns of gene expression leading to cell differentiation. Chromatin regulators control how the DNA is utilized by altering access of proteins to DNA and thereby function as co-factors in transcription. READ MORE

  6. 4. Transcription regulation across levels of chromatin organization

    Author : Roshan Vaid; Mattias Mannervik; Goncalo Castelo-Branco; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transcription; chromatin; epigenetics; Drosophila; embryo development; molekylär biovetenskap; Molecular Bioscience;

    Abstract : With advancements in high-throughput sequencing and high-resolution microscopy techniques, the significance of genome organization in transcription regulation is rapidly unveiling. Nonetheless, we are yet far from completely understanding this key relationship. READ MORE

  7. 5. Maf transcription factors in beta cell function

    Author : Elvira Ganic; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Beta cell; MafA; type 2 diabetes; insulin secretion; transcription; monoamine oxidase; MaoA; MaoB; nicotinic receptor subunits; nAChRs;

    Abstract : Diabetes mellitus is metabolic disorder caused by a defect or lack of beta cell-produced insulin that controls blood glucose homeostasis. In addition to glucose, insulin secretion is regulated by the autonomic nervous system (ANS); the neurotransmitter acetylcholine as well as monoamines, such as dopamine, serotonin, melatonin and norepinephrine. READ MORE