Search for dissertations about: "Transplantationskirurgi"

Showing result 1 - 5 of 6 swedish dissertations containing the word Transplantationskirurgi.

  2. 1. Minimizing Risks and Morbidity in Live Kidney Donors

    Author : Ali-Reza Biglarnia; Jonas Wadström; Gunnar Tufveson; Tomas Lorant; Ingela Fehrman-Ekholm; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; live donors; morbidity; GFR; donor nephrectomy; postoperative pain treatment; venous thromboembolism; HARS; Transplantation surgery; Transplantationskirurgi; Medicin; Medicine;

    Abstract : Live kidney donors are healthy volunteers who are exposed to major surgical procedure and physical harms with no direct therapeutic benefits. Efforts to minimize their risks and morbidity are therefore of utmost importance. READ MORE

  4. 2. The clinical perspective on malignancies in renal transplanted patients

    Author : Vivan Hellström; Tomas Lorant; Gunnar Tufveson; Gunilla Enblad; Per Lindnér; Uppsala universitet; []
    Keywords : renal transplantation; malignant tumours;

    Abstract : Post-transplant malignancies cause significant morbidity and mortality. In this thesis we investigated malignancies in renal transplanted patients from a clinical viewpoint. The use of regional tumour registries considerably improved identification of pre- and post-transplant malignancies, which are generally underreported in transplant registries. READ MORE

  5. 3. Studies of Rejection in Experimental Xenotransplantation

    Author : Tomas Lorant; Annika Tibell; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Antibodies; cell culturing; cytokines; hyaluronan; immunosuppression; mouse; rat; rejection; T lymphocytes; xenotransplantation.; Kirurgi; Surgery; Kirurgi; Surgery; Kirurgi;

    Abstract : One main hurdle to xenotransplantation, i.e. transplantation between different species, is the immunological barrier that the organ meets in the recipient. The aim of this thesis was to characterise xenogeneic rejection mechanisms by using the concordant mouse-to-rat heart transplantation model. READ MORE

  6. 4. Management of Ischemia and Brain Death-Associated Injuries in Porcine Kidney Grafts

    Author : Amir Sedigh; Tomas Lorant; Gunnar Tufveson; Olle Korsgren; Styrbjörn Friman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Organs from deceased donors after brain death (BD) remain the major source of organs for transplantation. The catastrophic event of BD and the inevitable consequences of ischemia reperfusion injury (IRI) are linked to impaired graft quality and transplantation outcome. READ MORE

  7. 5. Extracellular Matrix Based Materials for Tissue Engineering

    Author : Cecilia Aulin; Jöns Hilborn; Tim Bowden; Laura Creemers; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Extracellular matrix; collagen synthesis; bioreactor; cell culture; bone morphogenetic protein-2; noggin; hyaluronan; cartilage; Medical technology; Medicinsk teknik; Molecular biology; Molekylärbiologi; Orthopaedics; Ortopedi; Transplantation surgery; Transplantationskirurgi; Biomaterials; Biomaterial; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Cell and molecular biology; Cell- och molekylärbiologi; Polymer chemistry; Polymerkemi; Materials chemistry; Materialkemi; cellforskning; Cell Research; materialvetenskap; Materials Science; medicinsk cellbiologi; Medical Cell Biology; ortopedi; Orthopaedics;

    Abstract : The extracellular matrix is (ECM) is a network of large, structural proteins and polysaccharides, important for cellular behavior, tissue development and maintenance. Present thesis describes work exploring ECM as scaffolds for tissue engineering by manipulating cells cultured in vitro or by influencing ECM expression in vivo. READ MORE