Search for dissertations about: "Tumor immunity"

Showing result 1 - 5 of 109 swedish dissertations containing the words Tumor immunity.

  2. 1. Immune modulation in serous epithelial ovarian cancer : focus on the role of tumor-derived exosomes

    Author : Alireza Labani Motlagh; Lucia Mincheva-Nilsson; Ola Winqvist; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; EOC; HGSC; exosomes; NKG2D; MICA B; ULBP; DNAM-1; PVR; nectin-2; lncRNAs; immune suppression; anti-tumor immunity; NK-cell cytotoxicity; cytokines; Th1; Th2; T regulatory response; inflammation; tumor microenvironment;

    Abstract : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. READ MORE

  4. 2. Natural killer T (NKT) lymphocytes regulate of intestinal tumor immunity

    Author : Ying Wang; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NKT lymphocyte; intestinal tumor; CD1d; colrectal cancer; immunoregulation; α-gagactosylceramide;

    Abstract : CD1d-restricted natural killer T (NKT) lymphocytes are known as potent early regulatory cells of immune responses, acting as a bridge between innate and adaptive immunity. While invariant NKT (iNKT) cells have a protective role in many tumor models, their ability to promote intestinal inflammation, known to enhance intestinal cancer, raised the question if they would be protective in intestinal tumor development. READ MORE

  5. 3. Apoptosis in tumor immunity and immune evasion

    Author : Valentina Screpanti; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Apoptosis; Immune system;

    Abstract : .... READ MORE

  6. 4. Immunity and immunosuppression in the tumor-host interaction

    Author : Max Petersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Tumors; MHC class 1; natural processed peptides; T cells; NK cells; IFN-[gamma]; IL-10; TAP;

    Abstract : With the advent of new methods in molecular biology and in peptide isolation, a number of tumor-associated antigens and their epitopes have been identified and characterized. However, tumors often grow progressively evolving different mechanisms of immune escape, resulting in resistance to MHC class I-restricted tumor-specific T cells. READ MORE

  7. 5. Vascular Interactions in Innate Immunity and Immunothrombosis: : Models of Endothelial Protection

    Author : Sofia Nordling; Peetra Magnusson; Paul Kubes; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endothelial cells; Thrombosis; Innate immunity; Immunothrombosis; Thromboinflammation; Immunologi; Immunology;

    Abstract : The phenomenon known as immunothrombosis has garnered increased attention over the last few years. Much work has been done to characterize the cross talk between hemostasis and the innate immune system. READ MORE