Search for dissertations about: "U1A"

Found 3 swedish dissertations containing the word U1A.

2. 1. Rate Limiting Factors For Protein Folding

   Author : Maria Berggård Silow; Biokemi och Strukturbiologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; kinetic competition; transient aggregation; diffusion control; reconfiguration time; collapse; osmolytes; broad barriers; Hammond behaviour; two-state; U1A; CI2; Proteins; enzymology; Proteiner; enzymologi;

   Abstract : Abstract. This thesis describes factors that are rate limiting for the folding of two small proteins, U1A and CI2 which fold without accumulating intermediates. The [GdnHCl] dependencies of the unfolding- and refolding kinetics of U1A display downward curvatures. READ MORE

4. 2. Protein Folding Studied by Site Directed Mutagenesis

   Author : Tomas Ternström; Biokemi och Strukturbiologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Biokemi; metabolism; Biochemistry; Transition state; Activation Barrier; Two-State; Protein Folding; Protein Engineering;

   Abstract : The N-terminal RNA binding domain of U1A has been shown to fold in a two-state process without accumulating any intermediates. U1A has a symmetrically curved chevron plot which seems to result mainly from changes of the transition state. READ MORE

5. 3. The Folding Energy Landscape of MerP

   Author : Ann-Christin Brorsson; Bengt-Harald Jonsson; Daniel Otzen; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; protein folding and stability; hydrogen exchange; intermediate; partial unfolding; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

   Abstract : This thesis is based on studies, described in four papers, in which the folding energy landscape of MerP was investigated by various techniques. MerP is a water-soluble 72 amino acid protein with a secondary structure consisting of four anti-parallel β-strands and two α-helices on one side of the sheet in the order β1α1β2β3α2β4. READ MORE