Search for dissertations about: "UbC"

Showing result 1 - 5 of 10 swedish dissertations containing the word UbC.

  2. 1. Human Embryonic Stem Cells - Constitutive Gene Expression and Differentiation Towards Definitive Endoderm and Posterior Foregut Endoderm

    Author : Karin Norrman; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human embryonic stem cells; diabetes; pancreas; definitive endoderm; foregut endoderm; pancreatic endoderm; constitutive promoter; ACTB; EF1alpha; CMV; PGK; UbC;

    Abstract : Abstract More than 300 million people are suffering from diabetes worldwide and the numbers of diabetic patients are increasing. Today´s treatments mainly rely on daily insulin injections. This help people to control blood glucose levels but still many patients suffer from the many complications associated with diabetes. READ MORE

  4. 2. Bladder cancer. Urine tumour markers and hematuria

    Author : Hans Boman; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bladder neoplasm; bladder cancer; tumour markers in urine; hematuria; NMP 22; BTA stat; UBC; TPS; cytology;

    Abstract : Cancer of the urinary organs is one of the more common cancer forms in Sweden, with bladder cancer as the fourth most common cancer among men, and the seventh most common among women. The bladder cancer incidence is rising with age and is seldom seen before 50 years of age. READ MORE

  5. 3. T cells in solid tumors : investigating the immunomodulation in the tumor microenvironment

    Author : Ciputra Adijaya Hartana; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The immune system protects human from cancer through an immunosurveillance mechanism. However, the progressive nature of tumor cells to differentiate and the complexity of the tumor microenvironment may result in the immunomodulation of immune cells. READ MORE

  6. 4. Adaptive immunity in urothelial cancer : molecular and clinical aspects

    Author : David Krantz; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In the battle between the immune system and cancer, tolerance mechanisms otherwise protective against autoimmunity, are exploited to halt the anti-tumor immune response. In this model, tumors turn distinct parts of the immune system against each other; suppressive cells such as regulatory T cells (Tregs) are hijacked to obstruct effector lymphocytes in their attempt to eradicate the tumor. READ MORE

  7. 5. A valuable pair - candidate biomarkers RBM3 and PODXL in urothelial bladder cancer

    Author : Karolina Granfelt Boman; Tumörmikromiljö; []
    Keywords : urothelial bladder cancer; RBM3; PODXL; Prognostic biomarker; Predictive biomarker; immunohistochemistry; tissue microarray TMA ;

    Abstract : Abstract: Bladder cancer is a heterogenous disease, ranging from minimally invasive, low-grade tumours with lowrecurrence rates and mortality on one end of the spectrum, and muscle invasive, high-grade disease prone torecurrence, progression and death at the other end.The aim of this thesis was to investigate the expression, clinicopathological correlates and prognostic significanceof the candidate biomarkers podocalyxin-like protein (PODXL, papers II and III) and RNA-binding motif protein 3(RBM3, papers I, III and IV) in urothelial bladder cancer (UBC). READ MORE