Search for dissertations about: "V0 electrophoresis"

Found 2 swedish dissertations containing the words V0 electrophoresis.

2. 1. Adaptability of skeletal muscle to hormone treatment in relation to gender and aging

   Author : Fushun Yu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : skinned muscle fiber; gender; aging; steroid hormone; V0 electrophoresis; MyHC; MyLC; enzymehistochemistry; hyperthyroid rat; thyroid hormone receptor TR deficient TR[alpha]1 - -; TR[beta]- -; and TR[alpha]1- -[beta]- - mice;

   Abstract : The aims of this study were to investigate the expression of myosin isoforms, muscle contractility at the cell level, and changes in these parameters in response to altered hormonal status in aging male and female rodents. In addition, by using mice lacking thyroid hormone receptors (TR[alpha]1 or TR[beta] or TR[alpha]1/[beta]) we tried to improve our understanding of the mechanisms by which thyroid hormone regulates the expression of specific MyHC isoforms via these different nuclear receptors. READ MORE

4. 2. Effects of ageing on contractility and myosin composition of rat and man skeletal muscles and muscle cells : with special reference to muscle adaptability

   Author : Xiaopeng Li; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ageing; hyperthyroidism; skeletal muscle; single skinned fibre; isometric twitch; slack test; shortening velociy; electrophoresis; myosin isoform; immunocytochemistry;

   Abstract : The aims of this thesis were to characterize the effects of ageing on the contractile and biochemical properties of fast- and slow-twitch skeletal muscles at the whole muscle and single fibre level in an attempt to improve our understanding of the mechanisms underlying the age-related impairments of muscle fibres. Specific interest was in the adaptability of skeletal muscle and the regulation of speed of shortening at single-cell level in the rat and man. READ MORE