Search for dissertations about: "VSD"

Showing result 1 - 5 of 10 swedish dissertations containing the word VSD.

2. 1. Voltage sensor activation and modulation in ion channels

   Author : Christine S Schwaiger; Lindahl Erik; Paolo Carloni; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; activation; deactivation; inactivation; voltage sensor; VSD; gating; Kv1.2-2.1; Shaker; F233; hydrophobic barrier;

   Abstract : Voltage-gated ion channels play fundamental roles in neural excitability, they are for instance responsible for every single heart beat in our bodies, and dysfunctional channels cause disease that can be even lethal. Understanding how the voltage sensor of these channels function is critical for drug design of compounds targeting neuronal excitability. READ MORE

4. 2. Dynamics of the voltage-sensor domain in voltage-gated ion channels : Studies on helical content and hydrophobic barriers within voltage-sensor domains

   Author : Christine S. Schwaiger; Erik Lindahl; Lynn Kamerlin; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; activation; deactivation; inactivation; voltage-sensor; VSD; Kv1.2- 2.1; F233; hydrophobic barrier; alpha-helix; 3 10 -helix; Biological physics; Biologisk fysik;

   Abstract : Voltage-gated ion channels play fundamental roles in neural excitability and thus dysfunctional channels can cause disease. Understanding how the voltage-sensor of these channels activate and inactivate could potentially be useful in future drug design of compounds targeting neuronal excitability. READ MORE

5. 3. Synchronous Reluctance Machine (SynRM) in Variable Speed Drives (VSD) Applications

   Author : Reza Rajabi Moghaddam; Chandur Sadarangani; Alfredo Vagati; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Synchronous Reluctance Machine SynRM ; Torque; Torque Ripple; Design; Optimization; FEM; Control; Standard Size; Measurement; Performance Comparison; Induction Machine IM ; Interior Permanent Magnet Machine IPM ; Variable Speed Drive VSD ; General Purpose GP ; Field Oriented Control FOC ; Direct Torque Control DTC ; Heat Run; Test; Thermal; Operation Diagram; Circle Diagram; Electrical engineering; Elektroteknik;

   Abstract : This thesis is comprehensively dedicated to the theoretical and experimental reevaluation of the Synchronous Reluctance Machine (SynRM). A simple approach to derive the SynRM main characteristics and behavior is followed. An introduction to an evaluation of the different control strategies in is given. READ MORE

6. 4. Voltage-Sensor Domains of Ion Channels : Physiology, Regulation, and Role in Disease

   Author : Michelle Nilsson; Antonios Pantazis; Fredrik Elinder; Henry M. Colecraft; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Brain function depends on the ability of neurons to sense and respond to electricity, which is mediated by small modules in the neuronal membrane called voltage-sensor domains (VSDs). Disruption of VSD function can cause neurological disease such as epilepsy. READ MORE

7. 5. Conformational Changes during Potassium-Channel Gating

   Author : Jakob Renhorn; Fredrik Elinder; David Engblom; Stephan Pless; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ion-channel; electrophysiology; neuron; Jonkanal; neurologi; elektrofysiologi; neuron; aktionspotential;

   Abstract : Voltage-gated ion channels have a paramount importance in many physiological processes such as cell-to-cell communication, action potential-propagation, and cell motility. Voltage-gated ion channels are characterized by their ability to sense membrane voltage and to greatly change channel activity in response to small changes in the voltage. READ MORE