Search for dissertations about: "Vaccine"

Showing result 1 - 5 of 491 swedish dissertations containing the word Vaccine.

  2. 1. Heat shock proteins as vaccine adjuvants

    Author : Khaleda Rahman Qazi; Carmen Fernández; Qijun Chen; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heat shock protein; vaccine; adjuvant; BCG; Immunology; Immunologi;

    Abstract : New efficient vaccines against infectious diseases are in demand. Some important factors impeding the vaccine development are the poor immunogenicity and the MHC restriction of the immune responses to a number of antigens. READ MORE

  4. 2. Characterizing important flavivirus-host interactions : Replication, assembly, restriction factors and vaccine development

    Author : Pham Tue Hung Tran; Magnus Johansson; Wessam Melik; Naveed Asghar; Sören Andersson; Laurent Chatel-Chaix; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Flaviviruses; virus-host cell interaction; lunapark; ESCRT; ALIX; CHMP4A; ISG15; TRIMs; replicon virus-like particles; vaccine;

    Abstract : The genus Flavivirus (family Flaviviridae) consists of important zoonotic viruses that cause morbidity and mortality worldwide. These viruses are enveloped and have a positive-sense single-stranded RNA genome encoding a polyprotein. READ MORE

  5. 3. Development of a Cancer Vaccine Targeting Tumor Blood Vessels

    Author : Elisabeth J. M Huijbers; Anna-Karin Olsson; Arjan W. Griffioen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vaccine; Therapeutic; Cancer; Tumor; Angiogenesis; Immunization; Vascular; Extracellular matrix; Biomedicinsk laboratorievetenskap; Biomedical Laboratory Science; Medical Cell Biology; Medicinsk cellbiologi; Oncology; Onkologi; Medical Science; Medicinsk vetenskap;

    Abstract : A treatment strategy for cancer is the suppression of tumor growth by directing an immune response to the tumor vessels, which will destroy the tissue.In this thesis we describe the development of a vaccine that targets antigens expressed around angiogenic vasculature in most solid tumors. READ MORE

  6. 4. Broadly protective nanoparticle-based mucosal vaccine against influenza virus infection

    Author : Valentina Bernasconi; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucosal vaccination; Influenza A virus; CTA1-DD; Nanoparticle; Targeted adjuvant; Nasal immunization; Oral immunization; Neonatal vaccine; Universal vaccine;

    Abstract : Influenza is one of the major viral diseases affecting humans and it is responsible for three to five million cases of severe illness and about 250.000 to 500.000 deaths each year worldwide. READ MORE

  7. 5. Aspects of pertussis, pertussis vaccination and adverse events associated with aluminum adsorbed vaccines

    Author : Elisabet Bergfors; Göteborgs universitet; []
    Keywords : Pertussis; parapertussis; pertussis toxoid; vaccine; vaccination; vaccine trial; adjuvant; aluminium; adsorbed vaccines; adverse event; pruritic nodules; itching nodules; granuloma; sensitisation; hypersensitivity; contact allergy;

    Abstract : The thesis originates in a clinical study of one of the new acellular pertussis vaccines performed in Göteborg in the 1990s. The monocomponent vaccine, pertussis toxoid adsorbed to aluminium hydroxide, had previously been shown to have an efficacy of 71%. READ MORE