Search for dissertations about: "Vasculitis"

Showing result 1 - 5 of 50 swedish dissertations containing the word Vasculitis.

2. 1. Clinical and epidemiological Studies in ANCA-associated vasculitis

   Author : Jens Rathmann; Reumatologi och molekylär skelettbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vasculitis; ANCA vasculitis; Epidemiologi; Infection; Classification;

   Abstract : Objectives:This thesis aims to provide an overview of the epidemiology of AAV in southern Sweden, to evaluate different classification criteria in AAV. In addition we study if infection is a risk factor for later development of AAV comparing patients with AAV with a matched population cohort and to examine the occurrence of severe infections as an outcome in AAV. READ MORE

4. 2. Kinin System Activation in Vasculitis

   Author : Robin Kahn; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; kinin receptors; inflammation; vasculitis; proteinase 3; neutophils; anti-neutrophil-cytoplasmic antibodies; Kinin;

   Abstract : The kinin system is activated when high-molecular-weight kininogen (HK) is cleaved by plasma kallikrein thus generating bradykinin. Bradykinin is a potent proinflammatory peptide that induces plasma leakage, blood pressure drop, liberation of inflammatory cytokines and pain. READ MORE

5. 3. Studies on the Epidemiology and Outcome of Primary Systemic Vasculitis

   Author : Aladdin Mohammad; Njurmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; polyarteritis nodosa; survival; microscopic polyangiitis; arteritis; vasculitis damage index; Vasculitis; ANCA; Wegener s granulomatosis; Churg-Strauss syndrome;

   Abstract : Primary Systemic Vasculitides [PSV: Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), Churg-Strauss syndrome (CSS) and polyarteritis nodosa (PAN)] are rare systemic diseases of unknown etiology; if untreated, they are associated with high morbidity and mortality rates. Changes in the classification and diagnostic improvements during the last decades have increased reported prevalence and incidence rates of PSV. READ MORE

6. 4. The Balance between Pro- and Antiinflammatory Molecules in ANCA-Associated Vasculitis

   Author : Sophie Ohlsson; Njurmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrology; Urologi; nefrologi; Urology; monocyte; SLPI; proteinase 3; ANCA; vasculitis; inflammation;

   Abstract : ANCA-associated systemic vasculitis (AASV) is a group of inflammatory disorders, characterized by inflammation and necrosis of blood vessels and frequently granuloma formation. Patients with AASV make autoantibodies, so called ANCA, against proteins present in the granules of neutrophils and monocytes, mainly proteinase 3 (PR3) and myeloperoxidase (MPO). READ MORE

7. 5. Diagnostic and prognostic aspects of anti-neutrophil cytoplasmic antibodies in systemic vasculitis

   Author : Daina Selga; Njurmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serologi; serology; epitope; Wegener s granulomatosis; microscopic polyangiitis; polyarteritis nodosa; capture ELISA; Immunology; anti-neutrophil cytoplasmic antibody; proteinase 3; vasculitis; nephrology; Urologi; nefrologi; Urology;

   Abstract : Primary systemic vasculitis is associated with a high mortality if left untreated and it is essential to make the diagnosis before permanent organ damage has occurred. In this thesis the diagnostic and prognostic significance of anti-neutrophil cytoplasmic antibodies (ANCA) in systemic vasculitis is investigated. READ MORE