Search for dissertations about: "Wilms´ tumor gene 1"
Showing result 1 - 5 of 8 swedish dissertations containing the words Wilms´ tumor gene 1.
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1. The Wilms' tumor gene 1 (WT1) and leukemia -new insights and further complexity
Abstract : The Wilms tumor gene 1 (WT1) encodes a zinc-finger containing transcription factor which is highly expressed in immature hematopoietic progenitor cells. A high expression of WT1 and the presence of somatic mutations in acute leukemia indicate a role for WT1 in the pathogenesis of leukemia. READ MORE
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2. Significance of Wilms’ tumor gene 1 as a biomarker in acute leukemia and solid tumors
Abstract : Wilms’ tumor gene 1 (WT1) is a zinc finger transcriptional regulator with crucial functions in embryonic development. Originally WT1 was described as a tumor suppressor gene, but later studies have shown oncogenic properties of WT1 in a variety of tumors. Because of its dual functions in tumorigenesis, WT1 has been described as a chameleon gene. READ MORE
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3. Wilms' tumor gene 1 in different types of cancer
Abstract : The Wilms’ tumor gene 1 (WT1) was first reported as a tumor suppressor gene in Wilms’ tumor. However, later studies have shown the oncogenic properties of WT1 in a variety of tumors. It was recently proposed that WT1 was a chameleon gene, due to its dual functions in tumorigenesis. READ MORE
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4. Functional studies of Wilms’ tumor gene 1 (WT1) in hematopoiesis and leukemia
Abstract : Wilms’ tumor gene 1 (WT1) is a zinc-finger transcription factor that is involved in the development of urogenital organs and mesothelial tissues. It was initially identified as a tumor suppressor gene, based on the observation that somatic inactivation of the gene predispose for development of the pediatric kidney cancer Wilms’ tumor. READ MORE
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5. Mesothelial differentiation, mesothelioma and tumor markers in serous cavities
Abstract : Mesothelial cells covering the serous membranes are of mesodermal origin although they acquire several characteristics of epithelial cells. The cytological and histological diagnosis of malignant tumors in serous cavities is sometimes a major challenge: the main diagnostic alternatives are reactive benign mesothelium, mesothelioma and adenocarcinoma. READ MORE