Search for dissertations about: "Wistar"

Showing result 1 - 5 of 67 swedish dissertations containing the word Wistar.

  2. 1. Behavioral effects of female sex steroid hormones : models of PMS and PMDD in Wistar rats

    Author : Magnus Löfgren; Torbjörn Bäckström; Inga-Maj Johansson; Per Södersten; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; PMS; PMDD; rats; progesterone; estradiol; behavior; individual response; stress interaction; tolerance; withdrawal; learning and memory; anxiety.; Biological research on drug dependence; Biologisk beroendeforskning; Endocrinology; Endokrinologi; Obstetrics and gynaecology; Obstetrik och gynekologi; Pharmacological research; Farmakologisk forskning; Obstetrics and gynaecology; Obstetrik och gynekologi; Psychology; Psykologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Background Animal models can be used to mimic human conditions of psychopathology, and also as pre-clinical models to evaluate candidate drugs. With hormonal treatment it is possible to produce behavior in the rat which corresponds to the mental symptoms of pre-menstrual syndrome (PMS), and pre-menstrual dysphoric disorder (PMDD). READ MORE

  4. 2. Carbonate Ions and Gastric Cancer

    Author : Roy Ehrnström; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; ODC; COX-2; inflammation; Wistar rats; duodenogastric reflux; Medicin människa och djur ; proliferation; gastrojejunostomy; carbonate ions; Experimental gastric cancer;

    Abstract : Nearly one million new cases of gastric cancer are diagnosed annually throughout the world. Even though the incidence has fallen dramatically in recent decades, this disease is still the second leading cause of cancer death in a global perspective. READ MORE

  5. 3. About hyaluronan in the hypertrophic heart : studies on coordinated regulation of extracellular matrix signalling

    Author : Urban Hellman; Anders Waldenström; Stellan Mörner; Anna Engström-Laurent; Lena Jonasson; Umeå universitet; []
    Keywords : hyaluronan; hyaluronan synthases; gene expression; extracellular matrix; cardiac hypertrophy; rat wistar; male ; cardiomyocytes; growth factors; fibroblasts; microvesicles; exosomes; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Background. Myocardial hypertrophy is a risk factor for cardiovascular morbidity and mortality. Independent of underlying disease, the cardiac muscle strives in different ways to compensate for an increased workload. This remodelling of the heart includes changes in the extracellular matrix which will affect systolic and diastolic cardiac function. READ MORE

  6. 4. On the possible role of serotonin and angiotensin for the respiratory abnormalities observed in panic disorder and premenstrual dysphoria

    Author : Marie Olsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; panic disorder; premenstrual dysphoria; serotonin; paroxetine; PCPA; angiotensin; saralasin; respiration; respiratory variability; CO2; sodium lactate; female sex steroids; estrus cycle; Wistar rats;

    Abstract : Panic disorder and premenstrual dysphoria are accompanied by intriguing abnormalities related to the control of respiration, including enhanced responsiveness to CO2 and enhanced respiratory variability. These aberrations do not seem to be shared by other psychiatric disorders, but appear to be relatively unique for panic disorder and premenstrual dysphoria. READ MORE

  7. 5. Early Environment, Adolescent Alcohol Drinking and Neurobiological Responses to Drugs

    Author : Sara Palm; Ingrid Nylander; Anne-Lie Svensson; Lundblad Martin; Giancarlo Colombo; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescence; beta-endorphin; dopamine; dynorphin; endogenous opioids; enkephalin; high-speed chronoamperometry; housing conditions; maternal separation; multivariate concentric square field™ test; open field test; radioimmunoassay; voluntary alcohol intake; Wistar rats; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Genes and environment interact to determine an individual’s vulnerability or resilience to several psychiatric disorders, including alcohol use disorder (AUD). Alcohol use is often initiated during adolescence and early onset drinking is associated with increased risk for later AUD. READ MORE