Search for dissertations about: "acute lymphoblastic leukemia in children"
Showing result 1 - 5 of 31 swedish dissertations containing the words acute lymphoblastic leukemia in children.
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1. Acute lymphoblastic leukemia in Swedish children : clinical findings and treatment results
Abstract : .... READ MORE
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2. Gene Expression and DNA Methylation in Acute Lymphoblastic Leukemia
Abstract : Pediatric acute lymphoblastic leukemia (ALL) is the most common malignancy in children, which results from the malignant transformation of progenitor cells in the bone marrow into leukemic cells. The precise mechanisms for this transformation are not well defined, however recent studies suggest that aberrant regulation of gene expression or DNA methylation may play an important role. READ MORE
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3. Stem and progenitor cell involvement in acute lymphoblastic leukemia
Abstract : Leukemic stem cells (LSCs) share the capacity of self renewal and extensive proliferation with normal hematopoietic stem cells (HSCs), and are therefore obvious targets for therapy. As such, they need to be identified and characterized in order to elucidate what drives them, and what separates them from their normal counterparts. READ MORE
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4. Molecular Genetic Characterization of Acute Lymphoblastic Leukemia with a Poor Prognosis
Abstract : Acute lymphoblastic leukemia (ALL) affects individuals at all ages, with peak incidences in children 50 years. ALL is broadly categorized into B-cell precursor (BCP) and T-cell ALL with specific clinical features associated with outcome. READ MORE
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5. Minimal Residual Disease Assessment in Childhood Acute Lymphoblastic Leukemia
Abstract : Traditionally, response to treatment in hematological malignancies is evaluated by light microscopy of bone marrow (BM) smears, but due to more effective therapies more sensitive methods are needed. Today, detection of minimal residual disease (MRD) using immunological and molecular techniques can be 100 times more sensitive than morphology. READ MORE