Search for dissertations about: "adapter proteins"
Showing result 1 - 5 of 16 swedish dissertations containing the words adapter proteins.
-
1. Shb and Its Homologues: Signaling in T Lymphocytes and Fibroblasts
Abstract : Stimulation of the T cell receptor (TCR) induces tyrosine phosphorylation of numerous intracellular proteins, leading to activation of the interleukin-2 (IL-2) gene in T lymphocytes. Shb is a ubiquitously expressed adapter protein, with the ability to associate with the T cell receptor and several signaling proteins in T cells, including: the TCR ζ-chain, LAT, PLC-γ1, Vav, SLP-76 and Gads. READ MORE
-
2. Biochemical studies of the essential Clp protease in cyanobacteria and its associated adaptor proteins
Abstract : Proteins are an essential part of all organisms and are involved in many cellular processes. To regulate the function of proteins and facilitate their removal when damaged or otherwise compromised, sophisticated control systems have evolved that include molecular chaperones and proteases. READ MORE
-
3. BEN-solo proteins in genome architecture and function
Abstract : Eukaryotic genomes are organized in a complex manner inside the nucleus of each cell. Chromatin insulators are DNA elements that help to fold the linear DNA fiber in three-dimensional space and partition regulatory gene units. READ MORE
-
4. Studies on ITK-SYK signaling pathways
Abstract : Chromosomal alterations are frequent causes of cancer. Until now, SYK is reported in two different chromosomal translocation events generating the ITK-SYK-fusion protein in a subset of peripheral T cell lymphomas and the TEL-SYK fusion protein in a case of myelodysplastic syndrome. READ MORE
-
5. Studies on the transmembrane signaling of β1 integrins
Abstract : Integrins are heterodimeric cell surface receptors, composed of an α and a β subunit, mainly binding for extracellular matrix proteins. lntegrin subunit β1 can combine with at least 12 a subunits and thus form the biggest subfamily within the integrin family. READ MORE