Search for dissertations about: "adaptor proteins"

Showing result 1 - 5 of 54 swedish dissertations containing the words adaptor proteins.

  2. 1. Biochemical studies of the essential Clp protease in cyanobacteria and its associated adaptor proteins

    Author : Anders Tryggvesson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Clp-protease; Cyanaobacteria; adaptor proteins;

    Abstract : Proteins are an essential part of all organisms and are involved in many cellular processes. To regulate the function of proteins and facilitate their removal when damaged or otherwise compromised, sophisticated control systems have evolved that include molecular chaperones and proteases. READ MORE

  4. 2. Adaptor Proteins in Regulation of Receptor Endocytosis

    Author : Katarzyna Kowanetz; Carl-Henrik Heldin; Ivan Dikic; Ruth Palmer; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : Ligand-induced endocytosis of receptor tyrosine kinases (RTKs) is a dynamic process governed by numerous protein-protein and protein-lipid interactions. This is a major mechanism of signal termination and is also frequently impaired in cancer. READ MORE

  5. 3. The Relationship between Transmembrane Mucins, Ion Channels and PDZ Adaptor Proteins in the Small Intestine

    Author : Thaher Pelaseyed; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestine; mucin; MUC3; MUC17; SEA; PDZK1; GOPC; CFTR; NHE3;

    Abstract : The human body is continuously exposed to challenges from the surrounding world. In analogy with the skin, mucus is a well-organized and highly regulated barrier composed of polymeric and O-glycosylated mucins that protects luminal organs such as the gastrointestinal tracts from the outer milieu. READ MORE

  6. 4. Investigating histidine-rich glycoprotein and T cell-specific adaptor as potential biomarkers and therapeutic targets

    Author : Tor Persson Skare; Lena Claesson-Welsh; Mats Hellström; Elin Sjöberg; Jonas Fuxe; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Histidine-rich glycoprotein; T cell-specifik adaptor; Lymphoma; Glioblastoma; Vascular permeability;

    Abstract : The endothelial cell (EC), the most important cell type in blood vessels, lines the vessel wall and provides vessel integrity. EC function is tightly regulated, and its dysregulation is a key element in many diseases including cardiovascular disease, cancer and several diseases of the eye. READ MORE

  7. 5. Rewiring ret : PTB-adaptor regulated signaling and cell biology

    Author : T Kalle Lundgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The Ret receptor belongs to a group of transmembrane tyrosine kinase receptors that serve to transduce environmental signals into cellular responses. Upon extracellular ligand activation the receptors dimerize and their structural conformation is altered into one that allows for interaction with proteins in the cell cytosol. READ MORE