Search for dissertations about: "addiction heroin"

Showing result 1 - 5 of 6 swedish dissertations containing the words addiction heroin.

  1. 1. Preproenkephalin Gene and mRNA : Studies of Structure, Function, Cocaine Responses in an Animal Model, and Genetic Association with Human Opiate Addiction

    Author : Karl Steven LaForge; Fred Nyberg; Peter S. Eriksson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biological research on drug dependence; Neuropeptides; Endogenous opioid system; Drug addiction; Heroin; Cocaine; Gene expression; Genetic association; Biologisk beroendeforskning; Biological research on drug dependence; Biologisk beroendeforskning;

    Abstract : The endogenous opioid enkephalin neuropeptides are mediators of pain perception and have been implicated in human addictions. The preproenkephalin gene and its mRNA have also provided many examples of tissue- and species-specific variations in mRNA structure produced through a variety of transcriptional and post-transcriptional mechanisms. READ MORE

  2. 2. A National Swedish Methadone Program 1966-1989

    Author : Leif Grönbladh; Lars Gunne; Ulf Rydberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychiatry; heroin addiction; methadone maintenance treatment; rehabilitation; mortality; criminality and prostitution; retention; HIV-protection; treatment strategy; Psykiatri; Psychiatry; Psykiatri;

    Abstract : Methadone Maintenance treatment of compulsive opioid addiction was started by the study of Dole and Nyswander (1965) and has subsequently been replicated in programs throughout the world. Methadone treatment has become the most effective modality for the treatment of chronic heroin addiction. READ MORE

  3. 3. Improving maintenance treatment of heroin addiction : the role of buprenorphine

    Author : Karl Johan Kakko; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Heroin addiction is a condition with high morbidity and mortality. The discovery of Methadone Maintenance Treatment (MMT) by Dole and co-workers 1964 represented the first major advance in the treatment of this condition. Through the work of Gunne et al in Uppsala, MMT was implemented in Sweden already in 1966. READ MORE

  4. 4. Synaptic plasticity in drug abuse disorders : studies of the human post-mortem brain

    Author : Anna Ökvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Drug addiction is a chronic disorder characterized by craving and compulsive drug use despite adverse consequences and high rates of relapse during periods of abstinence. Therapeutic interventions for most addiction disorders are limited today, partly because the underlying neurobiology is still unknown. READ MORE

  5. 5. Evaluation of Naltrexone as a treatment for amphetamine dependence

    Author : Nitya Jayaram-Lindström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Amphetamine addiction is a disease that affects millions of people worldwide and lacks effective treatment. An estimated 35 million persons are reported to abuse amphetamines, which is more than the total number of cocaine and heroin abusers combined. READ MORE