Search for dissertations about: "adhesin of e.coli"
Showing result 1 - 5 of 19 swedish dissertations containing the words adhesin of e.coli.
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1. Molecular analysis of transcription factors in uropathogenic E. coli adhesin operons
Abstract : The main causative agent of human urinary tract infections is the uropathogenic Escherichia coli (UPEC) pathotype. It may cause disease due to its ability to express a number of bacterial virulence factors. Fimbrial adhesins are particularly important for the initial establishment of infection in the urinary tract. READ MORE
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2. Of spiders, bugs, and men : Structural and functional studies of proteins involved in assembly
Abstract : Protein assembly enables complex machineries while being economical with genetic information. However, protein assembly also constitutes a potential threat to the host, and needs to be carefully regulated.Sulfate is a common source of sulfur for cysteine synthesis in bacteria. READ MORE
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3. Combinatorial Synthesis of Pilicides
Abstract : This thesis describes a combinatorial approach to design and synthesis of three libraries of compounds, referred to as pilicides, designed to target periplasmic chaperones present in uropathogenic Escherichia coli bacteria that are the main cause of urinary tract infections. Periplasmic chaperones are required for assembly of adhesive organelles, i. READ MORE
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4. The role of the epithelial cell in Escherichia coli induced neutrophil migration into the urinary tract
Abstract : This study examined the molecular mechanisms of neutrophil migration to sites of mucosal bacterial infection. (1) Bacterial induction of neutrophil chemotactic cytokines and their role in neutrophil migration. Uropathogenic E. READ MORE
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5. Potent inhibitors of uropathogenic E. coli papG adhesins; Synthesis, conformational studies and biological evaluation of galabiose derivatives and synthesis of glycosphingolipid analogues
Abstract : The importance of carbohydrates in biological systems has become evident during the last fifty years. It is well known that pathogenic bacteria and viruses attach to glycoconjugates present at mammalian cell surfaces, and that this attachment is a prerequisite for the later stages of infection. READ MORE