Search for dissertations about: "adjuvant tamoxifen treatment"

Showing result 1 - 5 of 30 swedish dissertations containing the words adjuvant tamoxifen treatment.

  2. 1. Long-term effects of adjuvant tamoxifen treatment on cardiovascular disease and cancer

    Author : Johan Rosell; John Carstensen; Olle Stål; Bo Nordenskjöld; Lars Holmberg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adjuvant; adverse events; breast cancer; cerebrovascular disease; coronary heart disease; heart failure; lung cancer; second primary cancer; tamoxifen;

    Abstract : The aims of this thesis were to investigate the long-term effects of adjuvant tamoxifen treatment on breast cancer recurrence and mortality, cardiovascular disease, and the incidence of secondary cancer.Between 1982 and 1992, postmenopausal patients with early stage breast cancer were included in a randomized clinical study of 2 or 5 years of postoperative tamoxifen therapy. READ MORE

  4. 2. Predicting Prognosis and Tamoxifen Response in Breast Cancer. With a special focus on contralateral breast cancer

    Author : Sara Alkner; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; prognosis; treatment prediction; endocrine treatment; tamoxifen; coactivator; AIB1; PAX2; SRC; contralateral breast cancer; premenopausal; randomized trial; mode of detection; mammography.;

    Abstract : One of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. READ MORE

  5. 3. Cell cycle alterations and 11q13 amplification in breast cancer : prediction of adjuvant treatment response

    Author : Marie Ahnström Waltersson; Olle Stål; Marie-Louise Fjällskog; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The growth and development of the breast is to a large extent regulated by oestrogens through the oestrogen receptor (ER). Activation of the ERα triggers transcription of genes that are important for cell proliferation and stimulates entry into the G1 phase of the cell cycle. READ MORE

  6. 4. Prognostic and Predictive Markers in Primary Breast Cancer - Quality Assurance and Long-term Effects of Adjuvant tamoxifen Treatment

    Author : Maria Ekholm; Bröstcancer-genetik; []
    Keywords : Breast cancer; Quality assurance; Tamoxifen; Long-term effects;

    Abstract : .... READ MORE

  7. 5. Predictive markers for tamoxifen response in primary breast cancer

    Author : Maria Stendahl; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; General pathology; Cytologi; onkologi; prognosis; Cytology; oncology; cancerology; predictive marker; p27; cyclin D1; tamoxifen; PR; breast cancer; ER; pathological anatomy; Patologi allmän ; patologisk anatomi;

    Abstract : It is well-known that a majority of breast cancers are hormone-dependent, making endocrine therapy an important adjuvant treatment after surgery. Susceptibility to endocrine treatment is determined by the presence of estrogen receptors (ER) and progesterone receptors (PR) in the tumors. READ MORE