Search for dissertations about: "adverse drug interaction surveillance"

Showing result 1 - 5 of 6 swedish dissertations containing the words adverse drug interaction surveillance.

2. 1. Drug interaction surveillance using individual case safety reports

   Author : Johanna Strandell; Staffan Hägg; Niklas Norén; Andrew Bate; Robin E. Ferner; Linköpings universitet; []
   Keywords : Adverse drug reactions; adverse drug interaction surveillance; drug interactions; individual case safety reports; postmarketing pharmacovigilance; signal detection; MEDICINE; MEDICIN;

   Abstract : Background: Drug interactions resulting in adverse drug reactions (ADRs) represent a major health problem both for individuals and society in general. Post-marketing pharmacovigilance reporting databases with compiled individual case safety reports (ICSRs) have been shown to be particularly useful in the detection of novel drug - ADR combinations, though these reports have not been fully used to detect adverse drug interactions. READ MORE

4. 2. Statistical methods for knowledge discovery in adverse drug reaction surveillance

   Author : G. Niklas Norén; Rolf Sundberg; I. Ralph Edwards; Heikki Mannila; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mathematical statistics; Matematisk statistik; Mathematical Statistics; matematisk statistik;

   Abstract : Collections of individual case safety reports are the main resource for early discovery of unknown adverse reactions to drugs once they have been introduced to the general public. The data sets involved are complex and based on voluntary submission of reports, but contain pieces of very important information. READ MORE

5. 3. Studies on the halothane-diethyl-ether azeotrope

   Author : Sigga Kalman; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : Requirements for a safe standard for anaesthesia under primitiveconditions differ from those under peaceful circumstances. It is important not to blunt the reflexes that guard vital functions. READ MORE

6. 4. Atrial fibrillation after cardiac surgery : an analysis of risk factors, mechanisms, and survival effects

   Author : Giovanni Mariscalco; Bengt Åberg; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atrial fibrillation; adult; cardiac surgery; coronary artery bypass grafting; valvular surgery; cardiopulmonary bypass; mortalilty; histology; catecholamines; embolism; Surgery; Kirurgi;

   Abstract : Background: Despite the recent improvements in surgical techniques and postoperative patient care, atrial fibrillation (AF) remains the most frequent complication after cardiac surgery. Although postoperative AF is often regarded as a benign clinical condition, this arrhythmia has significant adverse effects on patient recovery and postoperative survival. READ MORE

7. 5. Novel combination chemotherapy for treatment and control of schistosomiasis among school children

   Author : Rajabu Hussein Mnkugwe; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Despite reported success in reducing severe disease-associated morbidities in endemic countries, praziquantel (PZQ) alone has failed to control and eliminate schistosomiasis, partly due to its poor efficacy against immature/juvenile worms. Artemisinin derivatives are efficacious against juvenile schistosomes. READ MORE