Search for dissertations about: "affibody-fusions"

Found 1 swedish dissertation containing the word affibody-fusions.

2. 1. Affibody ligands in immunotechnology applications

   Author : Jenny Rönnmark; KTH; []
   Keywords : phage display; combinatorial; affinity; IgA ligand; immunohistochemistry; affibody-fusions;

   Abstract : This thesis describes the development and use ofnon-immunoglobulin affinity proteins denoted affibodies asalternatives to antibodies in different immunotechnologyapplications. A 58 aa IgG Fc binding three-helix bundle domainZ, derived from staphylococcal protein A has been used asframework for library constructions, in which the face of themolecule involved in the native binding activity has beenengineered by combinatorial protein engineering. READ MORE