Search for dissertations about: "affinity-chromatography"
Showing result 1 - 5 of 81 swedish dissertations containing the word affinity-chromatography.
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1. Engineering Proteinaceous Ligands for Improved Performance in Affinity Chromatography Applications
Abstract : .... READ MORE
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2. Progress of Weak Affinity Chromatography as a Tool in Drug Development
Abstract : Weak Affinity Chromatography (WAC) is a technology that was developed to analyse weak (KD > 10-5 M) although selective interactions between biomolecules. The focus of this thesis was to develop this method for various applications in the drug development process.Fragment Based Drug Discovery is a new approach in finding new small molecular drugs. READ MORE
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3. Introducing weak affinity chromatography to drug discovery with focus on fragment screening
Abstract : Fragment-based drug discovery is an emerging process that has gained popularity in recent years. The process starts from small molecules called fragments. One major step in fragment-based drug discovery is fragment screening, which is a strategy to screen libraries of small molecules to find hits. READ MORE
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4. Insights into weak affinity antibody-antigen interactionsStudies using affinity chromatography and optical biosensor
Abstract : Molecular recognition and interaction is fundamental for the function of biological systems. The properties of the interacting biomolecules dictate the type of forces involved and the strength and dynamics of the interaction. Many interactions are very strong whereas others exhibit weak affinity. READ MORE
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5. Quantitation, Purification and Reconstitution of the Red Blood Cell Glucose Transporter GLUT1
Abstract : The human glucose transporter GLUT1 facilitates glucose to be accumulated on the other side of the cell membrane. The functional state of GLUT1 is uncertain due to diversity of the reports. In this thesis, the activity of red blood cell GLUT1 was extensively studied to further characterize this protein. READ MORE