Search for dissertations about: "alignments"
Showing result 1 - 5 of 75 swedish dissertations containing the word alignments.
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1. Politics and alignments in children's play dialogue : Play arenas and participation
Abstract : This thesis is about 6- and 8-year-old children's play dialogues, and its theoretical starting point is discourse analysis, on the one hand, and theories on play, on the other hand. The empirical basis is five studies on children's elicited and naturalistic play. All studies concern politics and relational alignments. READ MORE
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2. Methods and applications in DNA sequence alignments
Abstract : DNA sequence alignment is one of the most common bioinformatics tasks. Alignment analysis for eukaryotic genomes is challenging because the datasets are large. Repeat sequences also make the analysis difficult. This thesis describes new methods which we have developed for DNA sequence alignment that address these problems. READ MORE
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3. Algorithms for building and evaluating multiple sequence alignments
Abstract : The alignment of biological sequences is crucial for the transfer of annotation from model organisms to humans. Pairwise alignment of sequences can reveal homology while multiple alignments are used to characterize protein families and elucidate their evolutionary history. READ MORE
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4. Prediction, modeling, and refinement of protein structure
Abstract : Accurate predictions of protein structure are important for understanding many processes in cells. The interactions that govern protein folding and structure are complex, and still far from completely understood. However, progress is being made in many areas. Here, efforts to improve the overall quality of protein structure models are described. READ MORE
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5. The use of evolutionary information in protein alignments and homology identification
Abstract : For the vast majority of proteins no experimental information about the three-dimensional structure is known, but only its sequence. Therefore, the easiest way to obtain some understanding of the structure and function of these proteins is by relating them to well studied proteins. This can be done by searching for homologous proteins. READ MORE